Boehlecke B A, Merchant J A
Chest. 1981 Apr;79(4 Suppl):114S-122S. doi: 10.1378/chest.79.4_supplement.114s.
Pulmonary function testing and questionnaires are valuable tools in epidemiologic studies of occupational lung disease. Accurate equipment and standardized methodology are vital to obtain reproducible responses. For spirometry, the FVC and FEV show the least intrasubject variability and on questionnaires, occupational and smoking history are more reproducible than symptoms. The limitations of any method used to define a lower limit of normal should be kept in mind and, whenever possible, groups should be compared by use of the distribution of observations in the two groups--not just the prevalence of "abnormal" findings.
肺功能测试和问卷调查是职业性肺病流行病学研究中的重要工具。准确的设备和标准化方法对于获得可重复的结果至关重要。对于肺活量测定法，用力肺活量（FVC）和第一秒用力呼气容积（FEV）显示出受试者内部最小的变异性，而在问卷调查中，职业和吸烟史比症状更具可重复性。应牢记用于定义正常下限的任何方法的局限性，并且只要有可能，应通过两组观察值的分布来比较组，而不仅仅是“异常”结果的患病率。
