Lefevre F, O'Leary B, Moran M, Mossar M, Yarnold P R, Martin G J, Glassroth J
Division of General Internal Medicine, Northwestern University Medical School, Chicago, Illinois 60611, USA.
J Gen Intern Med. 1995 Aug;10(8):458-60. doi: 10.1007/BF02599920.
This prospective, cohort study analyzed the prevalence of alcoholism and patterns of alcohol intake over time in a cohort of HIV-infected patients, predominantly homosexual/bisexual men. One hundred eleven HIV-positive subjects were recruited from a comprehensive HIV clinic associated with a large Midwestern university hospital. Each participant completed the Michigan Alcoholism Screening Test (MAST) survey and a standardized quantity-frequency questionnaire on alcohol intake at enrollment. The quantity-frequency scale was repeated every six months for a total of 30 months. Forty-five of the 111 subjects (41%) met the criteria for alcoholism, as defined by a MAST score 5 or higher. There was a significant decrease in alcohol consumption over time, from 6.4 drinks/week in the initial time period to 3.9 drinks/week by the final time period (p < 0.001).
这项前瞻性队列研究分析了一组主要为同性恋/双性恋男性的HIV感染患者中酒精成瘾的患病率以及随时间变化的饮酒模式。从一所位于中西部的大型大学医院附属的综合HIV诊所招募了111名HIV阳性受试者。每位参与者在入组时完成了密歇根酒精成瘾筛查测试(MAST)调查以及一份关于饮酒情况的标准化数量频率问卷。数量频率量表每六个月重复一次,共持续30个月。111名受试者中有45名(41%)符合酒精成瘾标准,即MAST评分达到5分或更高。随着时间推移,酒精消费量显著下降,从最初阶段的每周6.4杯降至最后阶段的每周3.9杯(p < 0.001)。