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纤维肌痛中的疼痛应对机制:与疼痛及功能结果的关系

Pain coping mechanisms in fibromyalgia: relationship to pain and functional outcomes.

作者信息

Nicassio P M, Schoenfeld-Smith K, Radojevic V, Schuman C

机构信息

California School of Professional Psychology, San Diego 92121, USA.

出版信息

J Rheumatol. 1995 Aug;22(8):1552-8.

PMID:7473482
Abstract

OBJECTIVE

To evaluate the factor structure of the Coping Strategies Questionnaire (CSQ) in patients with fibromyalgia (FM) and to compare the factors derived from this measure, along with the active and passive pain coping scales of the Pain Management Inventory (PMI) in predicting pain, depression, quality of well being (QWB), and pain behavior concurrently and over time.

METHODS

One hundred twenty-two patients with FM were recruited from medical clinics, the community, and support groups. Eligible patients completed a battery of self-report measures of pain and psychosocial functioning at baseline assessment before random assignment to a clinical trial. A subset of 69 patients who completed the clinical trial were readministered the same battery 3 mo later. Data were analyzed within the baseline period, and from the baseline period to posttreatment to evaluate the predictive effects of coping strategies on clinical outcomes.

RESULTS

Principal components analysis of the CSQ revealed Coping Attempts (CA) and Pain Control and Rational Thinking (PCRT) factors, which have been found in other patient populations with chronic pain. Hierarchical multiple regression analyses revealed that high active coping and low PCRT contributed to higher concurrent pain, while low active coping and high passive coping were related to greater concurrent depression and pain behavior, respectively. Controlling for baseline scores on criterion measures, longitudinal multiple regression analyses demonstrated that high active coping and low PCRT scores contributed to greater pain, greater depression, and lower QWB at posttreatment, while low PCRT alone predicted greater pain behavior.

CONCLUSION

The results show the import of the pain coping construct in FM and highlight the negative contribution of low perceived control over pain and high active coping to a range of pain outcomes. The findings on low perceived control converge with data on other chronic pain populations, while the role of active coping appears to be detrimental in FM, in contrast to its positive effects in patients with rheumatoid arthritis.

摘要

目的

评估纤维肌痛(FM)患者应对策略问卷(CSQ)的因子结构,并比较该量表得出的因子,以及疼痛管理量表(PMI)的主动和被动疼痛应对量表在同时期及随访期对疼痛、抑郁、幸福感质量(QWB)和疼痛行为的预测作用。

方法

从医疗诊所、社区和支持小组招募了122例FM患者。符合条件的患者在随机分配至一项临床试验前,于基线评估时完成了一系列关于疼痛和心理社会功能的自我报告测量。69例完成临床试验的患者在3个月后再次接受相同的测量。在基线期内以及从基线期到治疗后对数据进行分析,以评估应对策略对临床结局的预测作用。

结果

CSQ的主成分分析揭示了应对尝试(CA)和疼痛控制与理性思维(PCRT)因子,这些因子在其他慢性疼痛患者群体中也有发现。分层多元回归分析显示,高主动应对和低PCRT与更高的同时期疼痛相关,而低主动应对和高被动应对分别与更严重的同时期抑郁和疼痛行为相关。在控制了标准测量的基线分数后,纵向多元回归分析表明,高主动应对和低PCRT分数在治疗后导致更严重的疼痛、更严重的抑郁和更低的QWB,而仅低PCRT可预测更严重的疼痛行为。

结论

结果显示了疼痛应对结构在FM中的重要性,并突出了对疼痛的低感知控制和高主动应对对一系列疼痛结局的负面作用。关于低感知控制的研究结果与其他慢性疼痛人群的数据一致,而主动应对的作用在FM中似乎是有害的,这与它在类风湿关节炎患者中的积极作用形成对比。

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