Alekseev A N, Burenkova L A, Podboronov V M, Chunikhin S P
Zoological Institute of Russian Academy of Sciences, St. Petersburg.
J Med Entomol. 1995 Sep;32(5):578-82. doi: 10.1093/jmedent/32.5.578.
The abundance of bacteriocidal compounds contained in the salivary cement plug of ixodid ticks was changed because of the reproduction of tick-borne encephalitis virus (TBEV) in their bodies. The size of TBEV-infected Ixodes persulcatus Shulze lytic zone surrounding the cement plug enlarged to that of naive ticks, whereas Micrococcus lysodeikticus (Cohn) lytic zones induced by the cement plugs of TBEV-infected Amblyomma hebraeum Koch nymphs or Rhipicephalus appendiculatus Neumann females were reduced, compared with those produced by noninfected specimens. It is possible that an increase of lysozyme production by the primary TBEV vectors (Ixodinae) infected salivary gland cells, compared with suppression of the bacteriocidal qualities of saliva of ticks that are not TBEV vectors in nature (Amblyomminae), is an indication of the specificity of a I. persulcatus-TBEV interface.
由于蜱传脑炎病毒（TBEV）在其体内繁殖，硬蜱唾液黏胶塞中所含杀菌化合物的丰度发生了变化。被TBEV感染的全沟硬蜱舒尔茨唾液黏胶塞周围的溶菌区大小扩大到了未感染蜱的水平，而与未感染标本所产生的溶菌区相比，被TBEV感染的希伯来花蜱若虫或微小扇头蜱雌虫唾液黏胶塞所诱导的溶壁微球菌溶菌区减小。与自然界中非TBEV传播媒介蜱（扇头蜱亚科）唾液杀菌特性受到抑制相比，主要TBEV传播媒介（硬蜱亚科）感染唾液腺细胞后溶菌酶产生增加，这可能表明全沟硬蜱与TBEV相互作用具有特异性。
