Alekseev A N, Burenkova L A, Podboronov V M, Chunikhin S P
Med Parazitol (Mosk). 1994 Oct-Dec(4):18-21.
It is demonstrated that the abundance of bactericidal compounds in the salivary cement plug of ixodid ticks is changing under the influence of virulent tick-borne encephalitis virus (TBEV) reproduction in their bodies. TBEV infected Ixodes persulcatus cement plug-forming lytic zone size enlarged in comparison with the naive tick one whereas Micrococcus lysodeikticus lytic zones induced by the cement plug of TBEV infected Amblyomma hebraeum nymphs or Rhipicephalus appendiculatus females reduced compared with produced by noninfected specimens. It is supposed that increasing of the lysozyme that production by the main TBEV vectors (Ixodinae ticks) infected salivary gland cells in comparison with suppression of the bactericidal qualities of saliva of the ticks which are not TBEV vectors in the nature (Amblyomminae ticks) is one of markers of the specificity of I. persulcatus-TBE virus interface.
结果表明，在硬蜱唾液粘胶塞中，杀菌化合物的丰度在其体内致病性蜱传脑炎病毒（TBEV）繁殖的影响下发生变化。与未感染的蜱相比，感染TBEV的全沟硬蜱形成粘胶塞的溶菌区大小增大；而感染TBEV的希伯来花蜱若虫或微小牛蜱雌蜱的粘胶塞诱导的溶壁微球菌溶菌区与未感染标本相比减小。据推测，主要TBEV传播媒介（硬蜱亚科蜱）感染唾液腺细胞产生的溶菌酶增加，而自然界中不是TBEV传播媒介的蜱（花蜱亚科蜱）唾液杀菌特性受到抑制，这是全沟硬蜱与TBE病毒相互作用特异性的标志之一。
