关于：一名结肠癌患者中NQO1（DT-黄递酶）点突变的检测 - Suppr

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Re: Detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer.

作者信息

Rosvold E A, McGlynn K A, Lustbader E D, Buetow K H

出版信息

J Natl Cancer Inst. 1995 Dec 6;87(23):1802-3. doi: 10.1093/jnci/87.23.1802.

DOI:10.1093/jnci/87.23.1802

PMID:7473840

Abstract

摘要

相似文献

Re: Detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer.关于：一名结肠癌患者中NQO1（DT-黄递酶）点突变的检测

J Natl Cancer Inst. 1995 Dec 6;87(23):1802-3. doi: 10.1093/jnci/87.23.1802.

Detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer.一名结肠癌患者中NQO1（DT-黄递酶）点突变的检测。

J Natl Cancer Inst. 1995 Jul 5;87(13):1022-4. doi: 10.1093/jnci/87.13.1022-a.

NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.人结肠癌细胞中NAD(P)H:醌氧化还原酶基因表达：调节DT-黄递酶活性和丝裂霉素敏感性的一种突变的特征

Cancer Res. 1992 Feb 15;52(4):797-802.

An alternatively spliced form of NQO1 (DT-diaphorase) messenger RNA lacking the putative quinone substrate binding site is present in human normal and tumor tissues.一种缺少假定的醌底物结合位点的NQO1（DT-黄递酶）信使核糖核酸可变剪接形式存在于人类正常组织和肿瘤组织中。

Cancer Res. 1995 Jun 15;55(12):2542-7.

A NAD(P)H:quinone oxidoreductase 1 polymorphism is a risk factor for human colon cancer.烟酰胺腺嘌呤二核苷酸磷酸（NAD(P)H）：醌氧化还原酶1基因多态性是人类结肠癌的一个风险因素。

Cancer Epidemiol Biomarkers Prev. 2006 Dec;15(12):2422-6. doi: 10.1158/1055-9965.EPI-06-0661.

A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.一种用于NAD(P)H:醌氧化还原酶（NQO1）导向的抗肿瘤醌类化合物的新型筛选系统：鉴定一种新型氮丙啶基苯醌RH1作为NQO1导向的抗肿瘤药物。

Clin Cancer Res. 1998 Dec;4(12):3083-8.

Lack of NQO1 induction in human tumor cells is not due to changes in the promoter region of the gene.人类肿瘤细胞中NQO1诱导作用的缺乏并非由于该基因启动子区域的变化。

Int J Oncol. 2002 Apr;20(4):835-8.

NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics.烟酰胺腺嘌呤二核苷酸磷酸（NAD(P)H）：醌氧化还原酶1（NQO1，DT-黄递酶）、功能及药物遗传学

Methods Enzymol. 2004;382:115-44. doi: 10.1016/S0076-6879(04)82008-1.

The NAD(P)H:quinone oxidoreductase locus in human colon carcinoma HCT 116 cells resistant to mitomycin C.人结肠癌HCT 116细胞中对丝裂霉素C耐药的NAD(P)H:醌氧化还原酶基因座

Cancer Res. 1996 Nov 15;56(22):5253-9.

[Polymorphism of NAD(P)H dehydrogenase (quinone) 1 (NQO1) C 609 T and risk of esophageal neoplasm].

Zhonghua Liu Xing Bing Xue Za Zhi. 2004 Aug;25(8):731.

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Clinicopathological implications of NQO1 overexpression in the prognosis of pancreatic adenocarcinoma.NQO1过表达在胰腺腺癌预后中的临床病理意义

Oncol Lett. 2017 May;13(5):2996-3002. doi: 10.3892/ol.2017.5821. Epub 2017 Mar 7.

NQO1 overexpression is associated with poor prognosis in squamous cell carcinoma of the uterine cervix.NQO1过表达与子宫颈鳞状细胞癌的不良预后相关。

BMC Cancer. 2014 Jun 9;14:414. doi: 10.1186/1471-2407-14-414.

Benzene, NQO1, and genetic susceptibility to cancer.苯、NQO1与癌症遗传易感性

Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7624-6. doi: 10.1073/pnas.96.14.7624.

Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy.常见的NAD(P)H醌氧化还原酶多态性患病率的种族差异及其对抗癌化疗的影响。

Br J Cancer. 1997;76(7):852-4. doi: 10.1038/bjc.1997.474.

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