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婴儿期长段气管狭窄的修复

Repair of long-segment tracheal stenosis in infancy.

作者信息

Jaquiss R D, Lusk R P, Spray T L, Huddleston C B

机构信息

Department of Surgery, Washington University School of Medicine, St. Louis, Mo, USA.

出版信息

J Thorac Cardiovasc Surg. 1995 Nov;110(5):1504-11; discussion 1511-2. doi: 10.1016/S0022-5223(95)70074-9.

DOI:10.1016/S0022-5223(95)70074-9
PMID:7475203
Abstract

Long-segment stenosis of the trachea in infancy is a considerable surgical challenge because the infants are generally extremely ill and the airway is small. The optimal type of repair is not clearly defined. This report summarizes our experience with rib cartilage tracheoplasty done with cardiopulmonary bypass. Six patients underwent repair of long-segment tracheal stenosis between September 1987 and September 1994. The mean age was 14 weeks (range 1 to 58 weeks). Patients had stenosis of at least 70% of the tracheal length, typically with complete cartilaginous rings. In all patients stenosis was repaired by placement of a section of rib cartilage as an augmentation patch into the anterior surface of the trachea, which had been incised through the entire length of the stenosis. To avoid distal airway intubation, we used cardiopulmonary bypass for all procedures, with a mean bypass duration of 110 minutes (range 54 to 175 minutes). Mechanical ventilation was required for a median of 11 days after the operation (range 7 to 81 days), and the median postoperative hospital stay was 17 days (range 12 to 180 days). All patients are long-term survivors. Complications included the need for extracorporeal membrane oxygenation to treat ventricular dysfunction in one patient and graft dehiscence requiring revision of the distal graft in another. The latter patient has required several treatments with a bronchoscope for removal of granulation tissue. All other patients are free of symptoms and have normal growth with a mean follow-up of 4.7 years (range 5 months to 7.6 years). We conclude that rib cartilage tracheoplasty for long-segment tracheal stenosis provides excellent results in short and intermediate follow-up. In addition, the use of cardiopulmonary bypass allows an unobstructed view of the tiny infant airway and thus permits a precise repair.

摘要

婴儿期气管长段狭窄是一项颇具挑战性的外科手术,因为婴儿通常病情极为严重且气道狭小。最佳的修复方式尚无明确定义。本报告总结了我们在体外循环下进行肋软骨气管成形术的经验。1987年9月至1994年9月期间,6例患者接受了长段气管狭窄修复术。平均年龄为14周(范围1至58周)。患者气管狭窄长度至少达70%,通常伴有完整的软骨环。所有患者均通过将一段肋软骨作为增强补片置于气管前表面来修复狭窄,气管在狭窄全长处被切开。为避免远端气道插管,我们对所有手术均采用体外循环,平均体外循环时间为110分钟(范围54至175分钟)。术后机械通气中位时间为11天(范围7至81天),术后住院中位时间为17天(范围12至180天)。所有患者均长期存活。并发症包括1例患者需要体外膜肺氧合治疗心室功能障碍,另1例患者移植片裂开,需要对远端移植片进行修复。后1例患者需要多次使用支气管镜清除肉芽组织。所有其他患者均无症状,生长正常,平均随访4.7年(范围5个月至7.6年)。我们得出结论,肋软骨气管成形术治疗长段气管狭窄在短期和中期随访中效果极佳。此外,使用体外循环可清晰观察微小的婴儿气道,从而实现精确修复。

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Repair of long-segment tracheal stenosis in infancy.婴儿期长段气管狭窄的修复
J Thorac Cardiovasc Surg. 1995 Nov;110(5):1504-11; discussion 1511-2. doi: 10.1016/S0022-5223(95)70074-9.
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Intermediate-term results of the free tracheal autograft for long segment congenital tracheal stenosis.游离气管自体移植治疗长段先天性气管狭窄的中期结果。
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引用本文的文献

1
Management of congenital tracheal stenosis: a multidisciplinary approach.先天性气管狭窄的管理:多学科方法
Images Paediatr Cardiol. 2000 Jan;2(1):29-39.
2
Surgical management of congenital tracheal stenosis.先天性气管狭窄的外科治疗
Gen Thorac Cardiovasc Surg. 2009 Apr;57(4):175-83. doi: 10.1007/s11748-008-0399-4. Epub 2009 Apr 15.