意大利人群中八种DNA多态性的等位基因和基因型频率。
Allele and genotype frequencies of eight DNA polymorphisms in the Italian population.
作者信息
Trabetti E, Galavotti R, Casartelli A, Magalini G, De Leo D, Pignatti P F
机构信息
Institute of Biology and Genetics, University of Verona, Italy.
出版信息
Mol Cell Probes. 1995 Jun;9(3):183-8. doi: 10.1006/mcpr.1995.0029.
We report the allele and genotype frequencies in Italians of eight unlinked commonly utilized polymorphic loci: HUMTH01, HUMFES/FPS, HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and GC. Genomic DNA from at least 100 individuals was amplified by PCR and typed after electrophoresis (HUMTH01, HUMFES/FPS), or reverse dot-blot (HLA-DQA1 and the other five loci). The allelic frequencies determined were compared with available population data. These results are useful for population and individual identification studies.
我们报告了八个不连锁的常用多态性位点在意大利人群中的等位基因和基因型频率，这些位点分别是：HUMTH01、HUMFES/FPS、HLA-DQA1、LDLR、GYPA、HBGG、D7S8和GC。从至少100名个体中提取的基因组DNA通过聚合酶链反应（PCR）进行扩增，然后通过电泳（HUMTH01、HUMFES/FPS）或反向斑点杂交（HLA-DQA1和其他五个位点）进行分型。将所确定的等位基因频率与现有的群体数据进行比较。这些结果对于群体和个体识别研究很有用。
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