Brito R M, Ribeiro T, Espinheira R, Geada H
Forensic Biology Laboratory, Institute of Legal Medicine, Lisbon, Portugal.
J Forensic Sci. 1998 Sep;43(5):1031-6.
Five South Portuguese Caucasian subpopulations were analyzed for the HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Gc loci. Genotype distributions for these loci did not deviate from Hardy-Weinberg expectations. The allele and genotype frequencies found have been compared with previously published data from North and Central Portugal. A total of 11 out of 138 chi-square comparisons of allele frequencies between different Portuguese populations showed a certain degree of divergence. Alentejo, Algarve, Madeira Island and Azores Islands populations might be considered as different groups in a database. For forensic casework, a composite South Portuguese Caucasian population database was obtained for estimating multiple locus profile frequencies using the six PCR-based loci studied.
对五个葡萄牙南部高加索亚群的HLA - DQA1、LDLR、GYPA、HBGG、D7S8和Gc基因座进行了分析。这些基因座的基因型分布未偏离哈迪-温伯格预期。所发现的等位基因和基因型频率已与葡萄牙北部和中部先前公布的数据进行了比较。在不同葡萄牙人群之间进行的138次等位基因频率卡方比较中，共有11次显示出一定程度的差异。在数据库中，阿连特茹、阿尔加维、马德拉岛和亚速尔群岛人群可被视为不同的群体。对于法医案件工作，利用所研究的六个基于PCR的基因座，获得了一个综合的葡萄牙南部高加索人群数据库，用于估计多位点图谱频率。
