希族塞人在Amplitype PM-DQA1和D1S80基因座的等位基因及基因型频率。
Greek Cypriot allele and genotype frequencies for Amplitype PM-DQA1 and D1S80 loci.
作者信息
Cariolou M A, Manoli P, Christophorou M, Bashiardes E, Karagrigoriou A, Budowle B
机构信息
Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory, Nicosia.
出版信息
J Forensic Sci. 1998 May;43(3):661-4.
A sample from the Greek Cypriot population was typed at seven forensically important PCR-based loci: LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, and D1S80. The results showed that all loci meet Hardy-Weinberg expectations and that there is no evidence for association of alleles between loci. Allelic frequency distributions at all loci, except HLA-DQA1 and two D1S80 alleles, were similar to those of U.S. Caucasians. Greek Cypriot population databases have been created and can be used for forensic analyses to estimate the frequency of a multiple locus DNA profile.
从塞浦路斯希腊族人群中采集的样本，在7个基于PCR的法医学重要基因座上进行了分型：低密度脂蛋白受体（LDLR）、血型糖蛋白A（GYPA）、血红蛋白Gγ（HBGG）、D7S8、组蛋白结合球蛋白（GC）、人类白细胞抗原-DQA1（HLA-DQA1）和D1S80。结果表明，所有基因座均符合哈迪-温伯格平衡预期，且没有证据表明基因座之间的等位基因存在关联。除HLA-DQA1和两个D1S80等位基因外，所有基因座的等位基因频率分布与美国白种人相似。已建立塞浦路斯希腊族人群数据库，可用于法医分析，以估计多位点DNA图谱的频率。
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