Suzuki K, Akai T, Sugita K, Sonobe M, Takahashi S
Department of Neurosurgery, Mito National Hospital.
No Shinkei Geka. 1995 Nov;23(11):981-4.
A sixty-two-year-old woman was diagnosed as having the mitral valve insufficiency seven months prior to admission. The patient was admitted to the hospital with complaints of right hemiparesis and aphasia. CT scan revealed an intracerebral hematoma in the left front-parietal region. Cerebral angiography disclosed an aneurysm at the distal portion of left middle cerebral artery. An increase in the amount of C reactive protein and leukocytosis indicated the presence of inflammatory lesions. Antibiotics were administered because a mycotic aneurysm was suspected. White blood cell count and C reactive protein returned to normal after treatment with antibiotics for one months. The aneurysm had disappeared on the second angiography performed after treatment. Strategy for mycotic aneurysm is still controversial. 49 reported cases in the literature since 1975 were reviewed and the efficiency of antibiotic therapy was discussed.
一名62岁女性在入院前7个月被诊断为二尖瓣关闭不全。该患者因右侧偏瘫和失语入院。CT扫描显示左额顶叶区域有脑内血肿。脑血管造影显示左大脑中动脉远端有一个动脉瘤。C反应蛋白量增加和白细胞增多表明存在炎症性病变。由于怀疑是霉菌性动脉瘤,给予了抗生素治疗。抗生素治疗1个月后白细胞计数和C反应蛋白恢复正常。治疗后进行的第二次血管造影显示动脉瘤已消失。霉菌性动脉瘤的治疗策略仍存在争议。回顾了自1975年以来文献报道的49例病例,并讨论了抗生素治疗的效果。