Brambilla F, Draisci A, Peirone A, Brunetta M
Centro di Psiconeuroendocrinologia, Ospedale Psichiatrico Pini, Milano, Italia.
Neuropsychobiology. 1995;32(2):68-71. doi: 10.1159/000119215.
Fifteen women with bulimia nervosa were treated with a 4-month course of combined cognitive-behavioral, nutritional and antidepressant therapy (5 with amineptine and 10 with fluvoxamine). Patients were monitored before and after 1, 2 and 4 months of therapy for body mass index (BMI), for eating disorder symptoms by the Eating Disorder Inventory (EDI) and the Bulimic Investigation Test (BITE), and for depression and anxiety by the Hamilton Rating Scale for Depression and for Anxiety (HRS-D and -A). BITE symptoms and gravity improved significantly and equally in the two groups during the 4 months of therapy. Global EDI scores, depression and anxiety decreased but not significantly. BMI was normal before therapy and did not change during treatment.
15名神经性贪食症女性接受了为期4个月的认知行为、营养和抗抑郁联合治疗（5名使用阿米替林，10名使用氟伏沙明）。在治疗前以及治疗1个月、2个月和4个月后，对患者的体重指数（BMI）、通过饮食失调量表（EDI）和贪食症调查测试（BITE）评估的饮食失调症状，以及通过汉密尔顿抑郁量表和焦虑量表（HRS-D和-A）评估的抑郁和焦虑情况进行监测。在4个月的治疗期间，两组的BITE症状和严重程度均显著且同等程度地改善。EDI总体评分、抑郁和焦虑有所下降，但不显著。治疗前BMI正常，治疗期间未发生变化。
