Baggish M S, Miklos J R
Department of Obstetrics and Gynecology, Good Samaritan Hospital, Cincinnati, Ohio 45220-2489, USA.
Obstet Gynecol Surv. 1995 Aug;50(8):618-27. doi: 10.1097/00006254-199508000-00023.
Vulvar pain syndrome (vulvar vestibulitis, vulvodynia, burning vulvar syndrome) was first described at the end of the last century. Although more than 100 years have passed, the cause(s) of the disorder remains elusive. This review of the literature endeavors to collate the known facts relating to vulvar pain syndrome and to expose those hypothetical etiologies which fall short of establishing any scientific foundation. The diagnosis of vulvar pain syndrome is established on the basis of historical data which detail a rather abrupt onset of vestibular itching, burning, dryness which may be intermittent or continuous. Commonly, patients present with a history of chronic treatment for recurrent fungal infections. Sexual relations become uncomfortable or intolerable. Unanimously, the patients describe a panorama of topical creams and ointments which fail to alleviate the symptoms. Physical examination typically verifies hyperesthesia of the vestibular skin when touched lightly with a cotton-tipped applicator. Similarly, the vestibular skin shows varying degrees of redness. The treatment programs for vulvar pain syndrome are as diverse as the multitude of etiological hypotheses. This review includes data pointing out those therapeutic measures that appear valueless and that may add to the patient's chronic discomfort.
外阴疼痛综合征（外阴前庭炎、外阴痛、外阴烧灼感综合征）于上世纪末首次被描述。尽管已过去100多年，但该疾病的病因仍不明了。这篇文献综述试图整理与外阴疼痛综合征相关的已知事实，并揭示那些缺乏科学依据的假设病因。外阴疼痛综合征的诊断基于病史，这些病史详细描述了前庭瘙痒、烧灼感、干燥等症状的突然发作，这些症状可能是间歇性或持续性的。通常，患者有反复真菌感染的慢性治疗史。性行为会变得不适或难以忍受。患者一致描述使用各种外用乳膏和软膏均无法缓解症状。体格检查通常通过用棉签轻触来验证前庭皮肤的感觉过敏。同样，前庭皮肤会出现不同程度的发红。外阴疼痛综合征的治疗方案与众多病因假说一样多样。这篇综述纳入了指出那些看似无效且可能加重患者慢性不适的治疗措施的数据。
