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莱姆病作为周围性面神经麻痹的病因:一项多中心研究。

Borreliosis as a cause of peripheral facial palsy: a multi-center study.

作者信息

Engervall K, Carlsson-Nordlander B, Hederstedt B, Berggren D, Bjerkhoel A, Carlborg A, Grenner J, Hanner P, Högmo A, Isholt R M

机构信息

Department of Otolaryngology, Słodersjukhuset, Stockholm, Sweden.

出版信息

ORL J Otorhinolaryngol Relat Spec. 1995 Jul-Aug;57(4):202-6. doi: 10.1159/000276740.

DOI:10.1159/000276740
PMID:7478454
Abstract

Borreliosis is known to be a common cause of peripheral facial palsy in Stockholm and its vicinity. The aim of the present study was to investigate the frequency and characteristics of borreliosis among patients with peripheral facial palsy in different parts of Sweden. All serological tests were performed in one laboratory. Ten Swedish Ear Nose and Throat clinics participated in a prospective 1-year study of patients seeking medical attention for acute peripheral facial palsy. Twenty-eight (6%) out of totally 446 patients fulfilled the criteria for the diagnosis of borreliosis. The frequency varied between 1 and 16% and was highest along the southeast coast of Sweden whereas no case was reported from the northern part of the country. Borreliosis was more common among children with facial palsy than among adults. The infection occurred during all seasons although it appears to be less frequent during the spring months. Only a minority of the borrelial patients had a history of a preceding tick bite or erythema migrans. The fairly low overall frequency of this secondary stage of borreliosis in the study may be a result of better knowledge of the disease and earlier treatment of its early manifestations. In Sweden's endemic areas borreliosis is a common cause of peripheral facial palsy, and therefore all patients with facial palsy in these regions should be examined for borrelial infection.

摘要

在斯德哥尔摩及其周边地区,莱姆病是周围性面神经麻痹的常见病因。本研究旨在调查瑞典不同地区周围性面神经麻痹患者中莱姆病的发病率及特征。所有血清学检测均在同一实验室进行。十家瑞典耳鼻喉诊所参与了一项为期一年的前瞻性研究,研究对象为因急性周围性面神经麻痹就医的患者。在总共446名患者中,有28名(6%)符合莱姆病的诊断标准。发病率在1%至16%之间,在瑞典东南沿海地区最高,而该国北部未报告病例。莱姆病在患有面神经麻痹的儿童中比在成人中更常见。尽管春季发病率似乎较低,但感染在所有季节均有发生。只有少数莱姆病患者有蜱虫叮咬或游走性红斑病史。本研究中莱姆病二期总体发病率较低,可能是由于对该病的了解增多以及对其早期症状的早期治疗。在瑞典的流行地区,莱姆病是周围性面神经麻痹的常见病因,因此这些地区所有面神经麻痹患者都应接受莱姆病感染检查。

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Clinical characteristics and cerebrospinal fluid parameters in patients with peripheral facial palsy caused by Lyme neuroborreliosis compared with facial palsy of unknown origin (Bell's palsy).
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