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Syntheses of N-alkyl-N-(hydroxy- or oxo-alkyl) nitrosamines related to N-butyl-N-(4-hydroxybutyl) nitroamine, a potent bladder carcinogen.

作者信息

Okada M, Suzuki E, Iiyoshi M

出版信息

Chem Pharm Bull (Tokyo). 1978 Dec;26(12):3891-6. doi: 10.1248/cpb.26.3891.

DOI:10.1248/cpb.26.3891
PMID:747856
Abstract
摘要

相似文献

1
Syntheses of N-alkyl-N-(hydroxy- or oxo-alkyl) nitrosamines related to N-butyl-N-(4-hydroxybutyl) nitroamine, a potent bladder carcinogen.与强致癌物质N-丁基-N-(4-羟基丁基)硝胺相关的N-烷基-N-(羟基或氧代烷基)亚硝胺的合成。
Chem Pharm Bull (Tokyo). 1978 Dec;26(12):3891-6. doi: 10.1248/cpb.26.3891.
2
Syntheses of N-alkyl-N-(omega-carboxyalkyl)nitrosamines related to N-butyl-N-(3-carboxypropyl)nitrosamine, principal urinary metabolite of a potent bladder carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine.与 N-丁基-N-(3-羧丙基)亚硝胺相关的 N-烷基-N-(ω-羧烷基)亚硝胺的合成,N-丁基-N-(3-羧丙基)亚硝胺是一种强效膀胱致癌物 N-丁基-N-(4-羟基丁基)亚硝胺的主要尿代谢产物。
Chem Pharm Bull (Tokyo). 1978 Dec;26(12):3909-13. doi: 10.1248/cpb.26.3909.
3
Metabolic fate of N-alkyl-N-(3-hydroxypropyl and 2-hydroxy-ethyl)nitrosamines in the rat in relation to the induction of bladder cancer by N-butyl-N-(4-hydroxybutyl)nitrosamine and its homologs.大鼠体内N-烷基-N-(3-羟丙基和2-羟乙基)亚硝胺的代谢命运与N-丁基-N-(4-羟丁基)亚硝胺及其同系物诱发膀胱癌的关系。
Gan. 1981 Apr;72(2):254-8.
4
Metabolic fate and carcinogenicity of N-(omega-hydroxyalkyl) N-(4-hydroxybutyl) nitrosamines analogs of N-butyl-N-(4-hydroxy-butyl) nitrosamine, in the rat.大鼠体内N-丁基-N-(4-羟丁基)亚硝胺的N-(ω-羟烷基)N-(4-羟丁基)亚硝胺类似物的代谢命运和致癌性
Gan. 1981 Aug;72(4):539-46.
5
Syntheses of N-(omega-acetoxyalkyl and omega-carbomethoxyalkyl)-N-(alpha-acetoxy-alkyl)nitrosamines, model compounds for possible metabolically activated N,N-dialkylnitrosamines.N-(ω-乙酰氧基烷基和ω-甲氧羰基烷基)-N-(α-乙酰氧基烷基)亚硝胺的合成,可能经代谢活化的N,N-二烷基亚硝胺的模型化合物。
Chem Pharm Bull (Tokyo). 1978 Dec;26(12):3914-9. doi: 10.1248/cpb.26.3914.
6
Metabolic fate of N-butyl-N-(4-hydroxybutyl)nitrosamine homologs in the rat, in relation to their organotropic carcinogenicity to the urinary bladder.大鼠体内 N-丁基-N-(4-羟基丁基)亚硝胺同系物的代谢命运,及其对膀胱的器官特异性致癌性
Gan. 1981 Feb;72(1):113-22.
7
Metabolic fate of N-butyl-N-(4-hydroxybutyl) nitrosamine and N, N-dibutylnitrosamine in the guinea pig, with reference to their carcinogenic effects on the urinary bladder.N-丁基-N-(4-羟丁基)亚硝胺和N,N-二丁基亚硝胺在豚鼠体内的代谢命运,及其对膀胱的致癌作用
Gan. 1981 Aug;72(4):547-51.
8
Carcinogenicity of N-nitrosamines related to N-butyl-N-(4-hydroxybutyl)nitrosamine and N,N,-dibutylnitrosamine in ACI/N rats.N-亚硝基胺与N-丁基-N-(4-羟基丁基)亚硝胺及N,N-二丁基亚硝胺在ACI/N大鼠中的致癌性
Gan. 1976 Dec;67(6):825-34.
9
Bladder carcinogenesis in mice induced by N-butyl-N-(4-hydroxybutyl) nitrosamine and N-ethyl-N-(4-hydroxybutyl)-nitrosamine with reference to the effect of cyclophosphamide.关于环磷酰胺的作用,N-丁基-N-(4-羟丁基)亚硝胺和N-乙基-N-(4-羟丁基)亚硝胺诱导的小鼠膀胱癌发生
Gan. 1981 Oct;72(5):647-54.
10
Relationship of urinary N-butyl-N-(3-carboxypropyl)nitrosamine to susceptibility of animals to bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.尿中N-丁基-N-(3-羧丙基)亚硝胺与动物对N-丁基-N-(4-羟丁基)亚硝胺诱发膀胱癌易感性的关系。
Gan. 1983 Jun;74(3):360-4.