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Syntheses of N-alkyl-N-(omega-carboxyalkyl)nitrosamines related to N-butyl-N-(3-carboxypropyl)nitrosamine, principal urinary metabolite of a potent bladder carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine.

作者信息

Okada M, Suzuki E, Iiyoshi M

出版信息

Chem Pharm Bull (Tokyo). 1978 Dec;26(12):3909-13. doi: 10.1248/cpb.26.3909.

DOI:10.1248/cpb.26.3909
PMID:747858
Abstract
摘要

相似文献

1
Syntheses of N-alkyl-N-(omega-carboxyalkyl)nitrosamines related to N-butyl-N-(3-carboxypropyl)nitrosamine, principal urinary metabolite of a potent bladder carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine.与 N-丁基-N-(3-羧丙基)亚硝胺相关的 N-烷基-N-(ω-羧烷基)亚硝胺的合成，N-丁基-N-(3-羧丙基)亚硝胺是一种强效膀胱致癌物 N-丁基-N-(4-羟基丁基)亚硝胺的主要尿代谢产物。
Chem Pharm Bull (Tokyo). 1978 Dec;26(12):3909-13. doi: 10.1248/cpb.26.3909.
2
Metabolic fate and carcinogenicity of N-(omega-hydroxyalkyl) N-(4-hydroxybutyl) nitrosamines analogs of N-butyl-N-(4-hydroxy-butyl) nitrosamine, in the rat.大鼠体内N-丁基-N-（4-羟丁基）亚硝胺的N-（ω-羟烷基）N-（4-羟丁基）亚硝胺类似物的代谢命运和致癌性
Gan. 1981 Aug;72(4):539-46.
3
Relationship of urinary N-butyl-N-(3-carboxypropyl)nitrosamine to susceptibility of animals to bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.尿中N-丁基-N-（3-羧丙基）亚硝胺与动物对N-丁基-N-（4-羟丁基）亚硝胺诱发膀胱癌易感性的关系。
Gan. 1983 Jun;74(3):360-4.
4
Metabolic fate of N-butyl-N-(4-hydroxybutyl)nitrosamine homologs in the rat, in relation to their organotropic carcinogenicity to the urinary bladder.大鼠体内 N-丁基-N-(4-羟基丁基)亚硝胺同系物的代谢命运，及其对膀胱的器官特异性致癌性
Gan. 1981 Feb;72(1):113-22.
5
Metabolic fate of N-butyl-N-(4-hydroxybutyl) nitrosamine and N, N-dibutylnitrosamine in the guinea pig, with reference to their carcinogenic effects on the urinary bladder.N-丁基-N-(4-羟丁基)亚硝胺和N,N-二丁基亚硝胺在豚鼠体内的代谢命运，及其对膀胱的致癌作用
Gan. 1981 Aug;72(4):547-51.
6
Syntheses of N-alkyl-N-(hydroxy- or oxo-alkyl) nitrosamines related to N-butyl-N-(4-hydroxybutyl) nitroamine, a potent bladder carcinogen.与强致癌物质N-丁基-N-(4-羟基丁基)硝胺相关的N-烷基-N-(羟基或氧代烷基)亚硝胺的合成。
Chem Pharm Bull (Tokyo). 1978 Dec;26(12):3891-6. doi: 10.1248/cpb.26.3891.
7
Carcinogenicity of N-nitrosamines related to N-butyl-N-(4-hydroxybutyl)nitrosamine and N,N,-dibutylnitrosamine in ACI/N rats.N-亚硝基胺与N-丁基-N-(4-羟基丁基)亚硝胺及N,N-二丁基亚硝胺在ACI/N大鼠中的致癌性
Gan. 1976 Dec;67(6):825-34.
8
Metabolic fate of N-alkyl-N-(3-hydroxypropyl and 2-hydroxy-ethyl)nitrosamines in the rat in relation to the induction of bladder cancer by N-butyl-N-(4-hydroxybutyl)nitrosamine and its homologs.大鼠体内N-烷基-N-(3-羟丙基和2-羟乙基)亚硝胺的代谢命运与N-丁基-N-(4-羟丁基)亚硝胺及其同系物诱发膀胱癌的关系。
Gan. 1981 Apr;72(2):254-8.
9
Species variations in the metabolism of N-butyl-N-(4-hydroxybutyl) nitrosamine and related compounds in relation to urinary bladder carcinogenesis.N-丁基-N-(4-羟基丁基)亚硝胺及相关化合物代谢的种属差异与膀胱癌发生的关系
Gan. 1983 Feb;74(1):60-8.
10
Comparative carcinogenicity of N-butyl-N-(3-carboxypropyl)-nitrosamine and N-butyl-N-(4-hydroxybutyl)nitrosamine for the urinary bladder of (C57BL/6 X DBA/2)F1 mice.N-丁基-N-(3-羧丙基)亚硝胺和N-丁基-N-(4-羟丁基)亚硝胺对(C57BL/6×DBA/2)F1小鼠膀胱的比较致癌性
J Natl Cancer Inst. 1984 Sep;73(3):753-6.

引用本文的文献

1
Differences in susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis between SD/gShi rats with spontaneous hypospermatogenesis and SD/cShi rats with spontaneous hydronephrosis.自发性精子发生低下的SD/gShi大鼠与自发性肾积水的SD/cShi大鼠对N-丁基-N-(4-羟丁基)亚硝胺诱导的膀胱癌发生易感性的差异。
Cancer Sci. 2005 Oct;96(10):637-44. doi: 10.1111/j.1349-7006.2005.00108.x.