Ljunghall S, Charles P, Falch J, Haug E, Melhus H, Mellström D, Mosekilde L, Pedersen J I, Sørensen O H, Toss G
Medicinkliniken, Akademiska Sjukhuset, Uppsala.
Nord Med. 1995;110(10):253-7.
Vitamin D constitutes a complex endocrine-regulated system, and is both a prohormone for the endogenous synthesis of the active hormone, calcitriol, and a vitamin which may be administered to supply the organism's requirements. No single test or investigation is available for the demonstration of vitamin D deficiency. Both vitamin D intake and ability to synthesise vitamin D decrease with increasing age, and particularly the elderly in institutionalised care are at risk of developing vitamin D deficiency. Iceland excepted, mean daily vitamin D consumption in the Nordic countries is less then 5 micrograms; and in approximately 10-25 per cent of the population, daily intake is less than 2.5 micrograms which is insufficient to maintain an adequate serum calcidiol concentration in individuals unexposed to sunlight. The recommended daily intake of 5 micrograms, currently adopted in the Nordic countries, may be too low-an intake of 10 micrograms is probably necessary to satisfy requirements in the elderly.
维生素D构成一个复杂的内分泌调节系统，它既是活性激素骨化三醇内源性合成的前体激素，也是一种可用于满足机体需求的维生素。目前尚无单一的检测或检查可用于证实维生素D缺乏。维生素D的摄入量和合成能力均随年龄增长而下降，尤其是接受机构护理的老年人有患维生素D缺乏症的风险。除冰岛外，北欧国家的平均每日维生素D摄入量低于5微克；约10%至25%的人口每日摄入量低于2.5微克，这不足以维持未接受阳光照射个体的血清骨化二醇浓度处于充足水平。北欧国家目前采用的每日推荐摄入量5微克可能过低——老年人可能需要摄入10微克才能满足需求。
