Delling G, Hahn M, Bonse U, Busch F, Günnewig O, Beckmann F, Uebbing H, Graeff W
Abt. Osteopathologie, Universität, Hamburg.
Pathologe. 1995 Sep;16(5):342-7. doi: 10.1007/s002920050112.
The combined histological and microcomputed analysis of human iliac crest biopsies leads to major advances in our understanding of three-dimensional bone architecture. Microcomputed tomography avoids the time-consuming reconstruction and artifacts of serial sections. Furthermore, its high resolution allows the recording of structural differences as low as 10 microns. Thus, three-dimensional analysis in combination with histological evaluation of cellular dynamics facilitates earlier and easier recording of changes of cancellous bone.
对人类髂嵴活检组织进行组织学和微型计算机分析相结合,使我们在理解三维骨结构方面取得了重大进展。微型计算机断层扫描避免了连续切片的耗时重建和伪影。此外,其高分辨率能够记录低至10微米的结构差异。因此,三维分析与细胞动力学的组织学评估相结合,有助于更早、更轻松地记录松质骨的变化。