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肥胖的非胰岛素依赖型糖尿病男性和女性通过减肥节省的药物费用。

Medication cost savings associated with weight loss for obese non-insulin-dependent diabetic men and women.

作者信息

Collins R W, Anderson J W

机构信息

Division of Internal Medicine, Veterans Affairs Medical Center, Lexington, Kentucky 40511, USA.

出版信息

Prev Med. 1995 Jul;24(4):369-74. doi: 10.1006/pmed.1995.1060.

Abstract

BACKGROUND

The cost of diabetes mellitus can be defined in both medical and economic terms. Although there is an abundance of literature concerning the medical management of diabetes, few studies have assessed the financial impact of its treatment. This study examined the savings in prescription costs associated with a weight reduction program for obese men and women with non-insulin-dependent diabetes mellitus (NIDDM).

RESEARCH DESIGN AND METHODS

Forty subjects ages 40-70 years who had body mass indexes of 30-40 kg/m2 and NIDDM of more than 1 year duration were assigned to one of two 800-kcal weight-loss programs for 12 weeks. A cost analysis was done on the 32 subjects who were taking anti-hypertensive and/or anti-diabetes medications. A list of medications and monthly amounts was obtained at the start, upon completion, and 1 year following completion of the diet. The average out-of-pocket cost for a month's supply of each prescription was calculated by polling 16 retail pharmacies in Lexington, Kentucky.

RESULTS

Subjects lost an average of 15.3 kg (33.7 lb) over the 12 weeks. At 1-year follow-up, subjects maintained a mean 9.0-kg (19.8 lb) weight loss. The average monthly prediet out-of-pocket cost for anti-hypertensive and anti-diabetes medications and supplies was $63.30 per subject. Following completion of the diet, this cost per month decreased to $20.40 and at 1-year follow-up the average monthly cost per subject was $32.40. The estimated average savings in prescription costs per subject over the year was $442.80.

CONCLUSIONS

Significant short- and long-term savings in prescription costs were obtained following a 12-week hypocaloric weight reduction program for obese individuals with NIDDM.

摘要

背景

糖尿病的成本可以从医学和经济两个方面来界定。尽管有大量关于糖尿病医学管理的文献,但很少有研究评估其治疗的财务影响。本研究调查了与非胰岛素依赖型糖尿病(NIDDM)肥胖男性和女性的减重计划相关的处方成本节省情况。

研究设计与方法

40名年龄在40 - 70岁、体重指数为30 - 40 kg/m²且NIDDM病程超过1年的受试者被分配到两个800千卡减重计划中的一个,为期12周。对32名正在服用抗高血压和/或抗糖尿病药物的受试者进行了成本分析。在饮食开始时、结束时以及结束后1年获取药物清单和每月用量。通过对肯塔基州列克星敦市的16家零售药店进行调查,计算出每个处方一个月供应量的平均自付费用。

结果

受试者在12周内平均减重15.3千克(33.7磅)。在1年随访时,受试者平均体重减轻维持在9.0千克(19.8磅)。抗高血压和抗糖尿病药物及用品的平均每月饮食前自付费用为每位受试者63.30美元。饮食结束后,该费用降至每月20.40美元,在1年随访时,每位受试者的平均每月费用为32.40美元。估计每位受试者一年内在处方成本上的平均节省为442.80美元。

结论

对于患有NIDDM的肥胖个体,经过12周的低热量减重计划后,在处方成本方面实现了显著的短期和长期节省。

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