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既往有紫外线红斑反应(I-IV 级)及经光试验(1-4 级)的白种人皮肤光型中的紫外线红斑敏感性:对新分类系统的需求

Ultraviolet erythema sensitivity in anamnestic (I-IV) and phototested (1-4) Caucasian skin phototypes: the need for a new classification system.

作者信息

Snellman E, Jansen C T, Leszczynski K, Visuri R, Milan T, Jokela K

机构信息

Department of Dermatology, Päijät-Häme Central Hospital, Lahti, Finland.

出版信息

Photochem Photobiol. 1995 Oct;62(4):769-72. doi: 10.1111/j.1751-1097.1995.tb08728.x.

DOI:10.1111/j.1751-1097.1995.tb08728.x
PMID:7480153
Abstract

The anamnestic skin phototypes (ASP) I-IV of 22 Caucasian volunteers wee compared with their phototested skin phototypes (PSP) using solar simulating, broadband UV radiation. The Commission Internationale de l'Eclairage (CIE)-weighted (i.e. erythemally effective) minimal erythema doses (MED) for solar simulating radiation varied from 20 mJ/cm2 (PSP type 1) to 57 mJ/cm2 (PSP type 4). In only 11 of 21 volunteers did the ASP (I-IV) and PSP (1-4) classifications coincide, and the MED values of the volunteers within the different ASP groups (I-IV) overlapped considerably. To compare the reactivity to erythematogenic radiation of different wavelengths, narrowband monochromator irradiations were performed at 298 nm, 310 nm and 330 nm. The CIE-weighted MED values at these wavelengths (20-80 mJ/cm2) corresponded well with those obtained in the broadband testing. Our results indicate that, with classification by interrogation, Caucasian skin can reliably be classified into only two subtypes, corresponding to Fitzpatrick phototypes I-III and phototype IV, respectively. A classification into four sensitivity types can be achieved by phototesting, only. We propose that the concept of ASP should be used with caution. The concept of PSP 1-4 should be favored.

摘要

使用太阳模拟宽带紫外线辐射,对22名白种人志愿者的记忆性皮肤光型(ASP)I-IV与其光测试皮肤光型(PSP)进行了比较。太阳模拟辐射的国际照明委员会(CIE)加权(即红斑有效)最小红斑剂量(MED)从20 mJ/cm²(PSP 1型)到57 mJ/cm²(PSP 4型)不等。在21名志愿者中,只有11人的ASP(I-IV)和PSP(1-4)分类一致,并且不同ASP组(I-IV)内志愿者的MED值有相当大的重叠。为了比较对不同波长致红斑辐射的反应性,在298 nm、310 nm和330 nm进行了窄带单色仪照射。这些波长下的CIE加权MED值(20 - 80 mJ/cm²)与宽带测试中获得的值非常吻合。我们的结果表明,通过询问进行分类时,白种人的皮肤只能可靠地分为两种亚型,分别对应于Fitzpatrick光型I-III和光型IV。只有通过光测试才能实现分为四种敏感性类型的分类。我们建议应谨慎使用ASP的概念。应优先采用PSP 1-4的概念。

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