Li Yu-Wen, Chu Chia-Yu
Department of Dermatology, Cathay General Hospital, Taipei, Taiwan.
J Formos Med Assoc. 2007 Nov;106(11):975-8. doi: 10.1016/S0929-6646(08)60071-6.
The purpose of this study was to determine the cutaneous response to UVB radiation in Taiwanese subjects. The relationships among minimal erythema dose (MED) of broadband UVB, Fitzpatrick's skin phototype, and skin color were examined in 61 healthy Taiwanese volunteers. Thirty-one females and 30 males were enrolled. Overall, the mean MED was 142.3 mJ/cm(2); there was no significant gender difference. The mean MEDs of subjects with Fitzpatrick skin types II, III, IV and V were 122.9 mJ/cm(2), 136.2 mJ/cm(2), 148.3 mJ/cm(2) and 165.0 mJ/cm(2), respectively. Both the mean MEDs and the lower MED limits increased with skin phototypes. To identify patients with abnormal photosensitivity, physicians could use these lower limits as reference values. In addition, different starting doses of broadband UVB phototherapy could be used for different skin phototypes.
本研究的目的是确定台湾受试者对紫外线B（UVB）辐射的皮肤反应。在61名健康的台湾志愿者中，研究了宽带UVB的最小红斑量（MED）、菲茨帕特里克皮肤光型和肤色之间的关系。招募了31名女性和30名男性。总体而言，平均MED为142.3 mJ/cm²；无显著性别差异。菲茨帕特里克皮肤光型为II、III、IV和V型的受试者的平均MED分别为122.9 mJ/cm²、136.2 mJ/cm²、148.3 mJ/cm²和165.0 mJ/cm²。平均MED和较低的MED下限均随皮肤光型增加。为了识别光敏性异常的患者，医生可以将这些下限用作参考值。此外，不同皮肤光型可使用不同起始剂量的宽带UVB光疗。
