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β-胡萝卜素在延长荷可移植性小鼠淋巴瘤宿主生存期方面的生理潜能。

Physiological potential of beta-carotene in prolonging the survival of the host bearing transplantable murine lymphoma.

作者信息

Ghosh B, Mandal A, Chatterjee M

机构信息

Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India.

出版信息

Planta Med. 1995 Aug;61(4):317-20. doi: 10.1055/s-2006-958091.

Abstract

beta-Carotene, when supplemented in diet, has been found to increase the survival period of mice bearing a transplantable tumor, Dalton's lymphoma. Tumor cell-count, body weight pattern, hematological parameters like total count showed marked alterations in a dose-responsive manner with beta-carotene administration when compared to their untreated counterparts. Decreased tumor cell proliferation is also reflected by increased hemoglobin levels of the host.

摘要

β-胡萝卜素在饮食中得到补充时,已被发现可延长携带可移植肿瘤——道尔顿淋巴瘤的小鼠的生存期。与未接受治疗的对照组相比,给予β-胡萝卜素后,肿瘤细胞计数、体重模式以及诸如全血细胞计数等血液学参数呈现出明显的剂量依赖性变化。宿主血红蛋白水平的升高也反映出肿瘤细胞增殖的减少。

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