希氏豆腐柴和少毛豆腐柴中二萜类化合物的细胞毒性。

Cytotoxicity of diterpenes from Premna schimperi and Premna oligotricha.

作者信息

Habtemariam S

出版信息

Planta Med. 1995 Aug;61(4):368-9. doi: 10.1055/s-2006-958105.

DOI:10.1055/s-2006-958105

Abstract

The cytotoxicity of two diterpenes from Premna schimperi and Premna oligotricha (Verbenaceae) was studied using the MTT assay. Their cytotoxic activity against three human (HeLa, SK.N.SH, and ECV 304) and two murine (L929 and RAW 264.7) carcinoma cell lines varied between 1.5 to 35 micrograms/ml and was comparable with azauridine and chlorambucil.

摘要

利用MTT法研究了来自唇形科植物施氏豆腐柴和少毛豆腐柴的两种二萜类化合物的细胞毒性。它们对三种人类癌细胞系（HeLa、SK.N.SH和ECV 304）和两种鼠类癌细胞系（L929和RAW 264.7）的细胞毒性活性在1.5至35微克/毫升之间变化，且与阿扎尿苷和苯丁酸氮芥相当。