Mutaf M, Tasaki Y, Arakaki M, Fujii T
Department of Plastic and Reconstructive Surgery, Nagasaki University School of Medicine, Japan.
Plast Reconstr Surg. 1995 Dec;96(7):1629-35. doi: 10.1097/00006534-199512000-00017.
A new composite free-flap model, namely, the saphenous artery osteomyocutaneous flap, is described in the rat. This is a true osteomyocutaneous flap composed of a skin island from the medial aspect of the lower leg, the gracilis and semitendinosus muscles, and a bone segment from the tibia based on the saphenous vascular pedicle. After anatomic studies in 10 rats, 20 flaps were transplanted microsurgically to the abdominal region in the recipient rats with a 90 percent success rate. In selected animals, arteriography was carried out. The results from gross observation of the flap survival and histologic and fluorochrome bone-labeling studies revealed a complete survival for each component of the flap in all animals with a patent vascular pedicle at 2 weeks after transfer. The model seems to be suitable for use in metabolic, vascular, and immunologic experimental studies on composite free flaps.
本文描述了一种新的复合游离皮瓣模型，即大鼠隐动脉骨肌皮瓣。这是一种真正的骨肌皮瓣，由小腿内侧的皮岛、股薄肌和半腱肌以及基于隐血管蒂的胫骨骨段组成。在对10只大鼠进行解剖学研究后，将20个皮瓣显微外科移植到受体大鼠的腹部区域，成功率为90%。对选定的动物进行了动脉造影。皮瓣存活的大体观察结果以及组织学和荧光骨标记研究表明，在转移后2周，所有动物中皮瓣的每个组成部分均完全存活，血管蒂通畅。该模型似乎适用于复合游离皮瓣的代谢、血管和免疫实验研究。
