Ostergaard M, Gideon P, Sørensen K, Hansen M, Stoltenberg M, Henriksen O, Lorenzen I
Danish Research Center of Magnetic Resonance, Hvidovre Hospital, University of Copenhagen, Denmark.
Scand J Rheumatol. 1995;24(4):212-8. doi: 10.3109/03009749509100876.
MRI-scores of synovial membrane hypertrophy and bone erosions of the RA-wrist are introduced. Gadolinium-DTPA enhanced magnetic resonance imaging (MRI) and conventional radiography (CR) of the wrist were performed in 16 patients with rheumatoid arthritis (RA) and 3 healthy controls. A MRI-score of synovial membrane hypertrophy was obtained by summation of gradings of synovial hypertrophy in 6 regions of the wrist. The score was significantly higher in wrists with than in wrists without clinical signs of active arthritis. The score was 0 in all healthy controls. Each bone of the wrist was assessed by MRI and CR with respect to bone erosions. Bone erosions were detected by MRI in 14 wrists in contrast to only 6 wrists by CR. In all patients the erosions were more numerous on MRI. The introduced methods may be useful quantitative measures of synovitis and early joint destruction in RA.
介绍了类风湿性关节炎（RA）手腕滑膜肥厚和骨质侵蚀的MRI评分。对16例类风湿性关节炎（RA）患者和3名健康对照者进行了钆喷酸葡胺增强磁共振成像（MRI）和手腕的传统放射摄影（CR）。通过对腕部6个区域滑膜肥厚的分级求和获得滑膜肥厚的MRI评分。有活动性关节炎临床体征的手腕的评分显著高于无该体征的手腕。所有健康对照者的评分为0。通过MRI和CR对腕部的每块骨头进行骨质侵蚀评估。通过MRI在14个手腕中检测到骨质侵蚀，相比之下CR仅在6个手腕中检测到。在所有患者中，MRI上的侵蚀更多。所介绍的方法可能是RA滑膜炎和早期关节破坏的有用定量测量方法。
