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马提尼克岛孕妇沙眼衣原体感染的筛查

Screening for Chlamydia trachomatis infection in pregnant women in Martinique.

作者信息

Chout R T, Vaton S, Duval-Violton D, Leguyader-Despres P, Orfila J

机构信息

Laboratory of Microbiology, Lamentin Hospital, Martinique, French West Indies.

出版信息

Sex Transm Dis. 1995 Jul-Aug;22(4):221-7. doi: 10.1097/00007435-199507000-00004.

Abstract

GOAL OF THIS STUDY

To determine the prevalence of Chlamydia trachomatis urogenital infection and to identify behavioral, demographic, and clinical factors associated with the infection in pregnant women in Martinique.

STUDY DESIGN

One-thousand-four-hundred-eleven patients 15-39 years old, at 10-16 weeks of gestation and attending the prenatal clinic at Lamentin Hospital, were tested for Chlamydia trachomatis infection of the cervix and urethra using tissue culture.

RESULTS

Chlamydia trachomatis was isolated from 375 (26.7%) women; 34% of them were positive in the cervix and urethra, 58% in the cervix only, and 8% in the urethra only. Factors found by multivariate analysis to be significantly associated with chlamydial infection were age less than 25 years, first intercourse at less than 18 years old, previous induced abortions, mucopurulent cervicitis, and repeated candidiasis.

CONCLUSIONS

None of the factors associated with chlamydial infection was sensitive enough to permit efficient selective screening. It is cost effective to recommend a routine screening for chlamydial infection together with an educational program.

摘要

本研究目的

确定马提尼克岛孕妇沙眼衣原体泌尿生殖系统感染的患病率,并识别与该感染相关的行为、人口统计学和临床因素。

研究设计

对1411名年龄在15至39岁之间、妊娠10至16周且在拉曼廷医院产前诊所就诊的患者,采用组织培养法检测宫颈和尿道的沙眼衣原体感染情况。

结果

从375名(26.7%)女性中分离出沙眼衣原体;其中宫颈和尿道均呈阳性的占34%,仅宫颈呈阳性的占58%,仅尿道呈阳性的占8%。多因素分析发现,与衣原体感染显著相关的因素包括年龄小于25岁、首次性交年龄小于18岁、既往人工流产史、黏液脓性宫颈炎和复发性念珠菌病。

结论

与衣原体感染相关的因素均不够敏感,无法实现有效的选择性筛查。推荐进行衣原体感染常规筛查并开展教育项目具有成本效益。

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