Oh M K, Cloud G A, Baker S L, Pass M A, Mulchahey K, Pass R F
Department of Pediatrics, University of Alabama School of Medicine, Birmingham 35294.
Sex Transm Dis. 1993 Jan-Feb;20(1):45-50. doi: 10.1097/00007435-199301000-00009.
Chlamydia trachomatis infection is one of the most common sexually transmitted diseases (STD) among adolescents and is one of the most common causes of perinatal infection. We have screened 267 young nulliparous adolescent girls (12-17 years old) for cervical C. trachomatis infection during their pregnancy using tissue culture methods. The population was a cohort of pregnant teenagers who had limited sexual exposure (mean duration of sexual activity, 14.3 months, mean number of lifetime partners, 2.0 +/- 1.5). The initial screening was done at enrollment to a prenatal care clinic, and the third trimester examination at 32 to 36 weeks of gestation. According to clinical indications, additional interim STD examinations were carried out. The cervical C. trachomatis infection rate was 18.7% (50/267) at intake and 7.9% (14/178) in the third trimester. Three of the 40 interim STD examinations also were positive for cervical C. trachomatis infection. Prenatally, 64 of 267 (24.0%) girls were positive for C. trachomatis at one or more times. The repeat culture positive rate for C. trachomatis was 7.8% (17/218), and 14 of those that were negative on the initial screening were positive on the subsequent screening. One or more types of treatable STDs (chlamydial, gonorrhea, syphilis, or trichomonal) were identified in 38.6% (103/267) of the study population during pregnancy. These findings suggest that high-risk sexual behavior may continue in teen pregnancy, and repeated prenatal chlamydial and other STD screening and counseling are indicated in this population.
沙眼衣原体感染是青少年中最常见的性传播疾病（STD）之一，也是围产期感染的最常见原因之一。我们采用组织培养方法，对267名未生育的年轻青春期女孩（12 - 17岁）在孕期进行了宫颈沙眼衣原体感染筛查。研究人群为一群性接触有限的怀孕青少年（性活动平均持续时间为14.3个月，性伴侣终生平均数量为2.0 +/- 1.5）。初始筛查在产前护理诊所登记时进行，孕晚期检查在妊娠32至36周时进行。根据临床指征，还进行了额外的中期STD检查。入组时宫颈沙眼衣原体感染率为18.7%（50/267），孕晚期为7.9%（14/178）。40次中期STD检查中有3次宫颈沙眼衣原体感染也呈阳性。产前，267名女孩中有64名（24.0%）在一次或多次检查中沙眼衣原体呈阳性。沙眼衣原体重复培养阳性率为7.8%（17/218），其中14名初始筛查阴性的女孩在后续筛查中呈阳性。在孕期研究人群中，38.6%（103/267）被发现有一种或多种可治疗的STD（衣原体、淋病、梅毒或滴虫）。这些发现表明，青少年怀孕时可能会继续存在高危性行为，该人群需要反复进行产前衣原体和其他STD筛查及咨询。
