Benacka J, Mális F, Zlnay D
Interné oddelenie NsP, Piest'any.
Vnitr Lek. 1995 Sep;41(9):613-7.
The authors subjected to complete echocardiographic examination 40 patients with ankylosing spondylitis (AS) in order to assess pathological changes of the heart (changes of the structure and function of valves, myocardial function of the left ventricle and the pericardium) and compare their incidence with clinical characteristics of the patients (age, duration, stage, form and activity of the disease) as well as with the presence of ECG changes. Based on the results and their statistical analysis they revealed that structural changes of the aorta and its valves associated with dilatation of the root of the aorta, its mild insufficiency and the possible finding of a typical bump on its posterior wall is found in half the patients with AS, being more frequent when the disease develops early, when it persists for a long time or is in an advanced stage. A similar relationship is found also in the presence of mild diastolic dysfunction of the left ventricle. The authors did not observe a more frequent incidence of other pathological changes of the heart in patients with AS. None of the detected changes were clinically severe and did not call for aimed treatment or surgery. In the conclusion the authors compare the assessed facts with data in the literature and confront data in the literature.
作者对40例强直性脊柱炎（AS）患者进行了完整的超声心动图检查，以评估心脏的病理变化（瓣膜结构和功能变化、左心室心肌功能及心包情况），并将其发生率与患者的临床特征（年龄、病程、分期、疾病类型及活动度）以及心电图变化情况进行比较。基于检查结果及其统计分析，他们发现，在半数AS患者中可发现主动脉及其瓣膜的结构变化，表现为主动脉根部扩张、轻度关闭不全，且后壁可能出现典型凸起，疾病早期发病、病程较长或处于晚期时更为常见。左心室轻度舒张功能障碍的情况也存在类似关系。作者未观察到AS患者心脏其他病理变化的发生率更高。所检测到的变化均无临床严重性，无需针对性治疗或手术。在结论部分，作者将评估的事实与文献数据进行了比较，并对文献数据进行了对照。
