Leugers C M, Clover R
Department of Family Medicine, University of Texas Medical Branch, Galveston 77555-0853, USA.
J Am Board Fam Pract. 1995 Sep-Oct;8(5):384-91.
Lemierre syndrome, or postanginal sepsis, was first described in the early part of this century and is characterized by pharyngitis, followed by high fever and rigors, cervical adenopathy, thrombophlebitis of the internal jugular vein, distant abscess formation, and icterus, associated with isolation of Fusobacterium necrophorum from blood.
This report describes a case of postanginal sepsis and reviews the medical literature on postanginal sepsis obtained through the MEDLINE data base using Fusobacterium as the key search word.
The features of Lemierre syndrome have changed little since the original description, through the prognosis has improved dramatically since the development of antibiotics. Appropriate management includes prompt administration of an antibiotic with good anaerobic coverage, drainage of persistent abscesses, and continued antibiotic therapy until radiographic resolution of abscess is achieved.
Although Lemierre syndrome is a relatively uncommon disease, the primary care physician needs to be aware of the clinical features and management to treat appropriately.
勒米尔综合征，即咽后败血症，于本世纪初首次被描述，其特征为咽炎，继以高热和寒战、颈部腺病、颈内静脉血栓性静脉炎、远处脓肿形成及黄疸，并伴有从血液中分离出坏死梭杆菌。
本报告描述了一例咽后败血症病例，并回顾了通过MEDLINE数据库以梭杆菌为关键词检索到的关于咽后败血症的医学文献。
自最初描述以来，勒米尔综合征的特征变化不大，不过自抗生素出现后，其预后已显著改善。恰当的处理包括迅速给予具有良好厌氧菌覆盖范围的抗生素、引流持续存在的脓肿，以及持续进行抗生素治疗直至脓肿在影像学上消退。
尽管勒米尔综合征是一种相对罕见的疾病，但基层医疗医生需要了解其临床特征及处理方法以便进行恰当治疗。
