• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

具核梭杆菌性心内膜炎:一例报告及文献综述

Fusobacterium nucleatum endocarditis: a case report and literature review.

作者信息

Dhaliwal Deepak, Bhargava Rishi, Movahed Mohammad Reza

机构信息

CareMore Health Tucson, Arizona, USA.

University of Arizona Server Heart Center Tucson, Arizona, USA.

出版信息

Am J Cardiovasc Dis. 2023 Feb 15;13(1):29-31. eCollection 2023.

PMID:36938520
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10017923/
Abstract

Fusobacteria is anaerobic gram-negative rods, which frequently colonize the oral cavity and can rarely cause deadly diseases in humans. The two most commonly found in this group of bacteria are fusobacterium necrophorum and fusobacterium nucleatum. Only a handful of cases of endocarditis due to fusobacterium have been reported. We describe an 86-year-old male who had a recent tooth extraction presenting to the emergency department with weakness lightheadedness, and pain in his right elbow. He had a low-grade fever of 100.8°. The patient was discharged home but came back less than 24 hours with a fever of 102° and chills and again after the second discharge with sepsis of unknown origin. A week after initial blood cultures were drawn, fusobacterium nucleatum grew in one of two sets and his transesophageal echocardiogram revealed vegetation on his mitral valve. The patient was then successfully treated with a six weeks course of ampicillin-sulbactam. This case is followed by a review of the literature.

摘要

梭杆菌属是革兰氏阴性厌氧菌,常定植于口腔,极少在人类中引发致命疾病。该组细菌中最常见的两种是坏死梭杆菌和具核梭杆菌。仅有少数几例由梭杆菌引起的心内膜炎病例报告。我们描述了一名86岁男性,他近期拔牙后因虚弱、头晕和右肘疼痛前往急诊科就诊。他有低热,体温为100.8°。患者出院回家,但不到24小时后因发热102°和寒战再次就诊,第二次出院后又因不明原因的败血症再次就诊。首次采集血培养一周后,具核梭杆菌在两组血培养中的一组中生长,经食管超声心动图显示其二尖瓣上有赘生物。该患者随后成功接受了为期六周的氨苄西林-舒巴坦治疗。本文随后对相关文献进行了综述。

相似文献

1
Fusobacterium nucleatum endocarditis: a case report and literature review.具核梭杆菌性心内膜炎:一例报告及文献综述
Am J Cardiovasc Dis. 2023 Feb 15;13(1):29-31. eCollection 2023.
2
First case of Fusobacterium necrophorum endocarditis to have presented after the 2nd decade of life.坏死梭杆菌性心内膜炎首例发病于生命的第二个十年之后。
Tex Heart Inst J. 2013;40(4):449-52.
3
A Rare Case of Cerebral Abscess due to with Native Aortic Valve Infective Endocarditis and Pyogenic Liver Abscess.罕见的由 引起的脑脓肿合并 native aortic valve infective endocarditis 和化脓性肝脓肿。
J Investig Med High Impact Case Rep. 2024 Jan-Dec;12:23247096241272014. doi: 10.1177/23247096241272014.
4
Two cases of diskitis attributable to anaerobic bacteria in children.两例儿童厌氧细菌所致椎间盘炎
Pediatrics. 2001 Feb;107(2):E26. doi: 10.1542/peds.107.2.e26.
5
[Necrotising endocarditis of mitral valve due to Staphylococcus lugdunensis].[路邓葡萄球菌所致二尖瓣坏死性心内膜炎]
Mikrobiyol Bul. 2009 Apr;43(2):319-23.
6
A discrepant presentation of bacteremia in the emergency department linked to a Fusobacterium nucleatum infection: a case report.急诊科中表现不一致的菌血症与核梭杆菌感染相关:一例病例报告。
J Med Case Rep. 2022 Jan 4;16(1):16. doi: 10.1186/s13256-021-03208-3.
7
[A case of liver abscess caused by Fusobacterium nucleatum in a patient with recurrent periodontal diseases].[1例由具核梭杆菌引起的肝脓肿病例,患者患有复发性牙周疾病]
Korean J Gastroenterol. 2011 Jan;57(1):42-6. doi: 10.4166/kjg.2011.57.1.42.
8
Fusobacterium necrophorum endocarditis Case report and review of the literature.坏死梭杆菌心内膜炎病例报告及文献复习。
Diagn Microbiol Infect Dis. 2011 Feb;69(2):192-5. doi: 10.1016/j.diagmicrobio.2010.09.014.
9
[Right-sided endocarditis due to Fusobacterium nucleatum].[具核梭杆菌引起的右侧心内膜炎]
Rev Esp Cardiol. 1991 Mar;44(3):207-9.
10
Fusobacterium necrophorum Endocarditis with Liver Abscesses: A Case Report and Review of the Literature.坏死梭杆菌心内膜炎合并肝脓肿:病例报告及文献复习。
Intern Med. 2021 Aug 1;60(15):2445-2449. doi: 10.2169/internalmedicine.6348-20. Epub 2021 Mar 1.

引用本文的文献

1
Infective Endocarditis by Species-A Systematic Review.按物种分类的感染性心内膜炎——一项系统评价
Pathogens. 2025 Aug 21;14(8):829. doi: 10.3390/pathogens14080829.
2
Human oral microbiome and its influence on mental health and brain disorders.人类口腔微生物群及其对心理健康和脑部疾病的影响。
AIMS Microbiol. 2025 Apr 14;11(2):242-294. doi: 10.3934/microbiol.2025013. eCollection 2025.
3
Exploring links between oral health and infective endocarditis.探索口腔健康与感染性心内膜炎之间的联系。
Front Oral Health. 2024 Dec 2;5:1426903. doi: 10.3389/froh.2024.1426903. eCollection 2024.

本文引用的文献

1
in the Colorectum and Its Association with Cancer Risk and Survival: A Systematic Review and Meta-analysis.在结直肠及其与癌症风险和生存的关系:系统评价和荟萃分析。
Cancer Epidemiol Biomarkers Prev. 2020 Mar;29(3):539-548. doi: 10.1158/1055-9965.EPI-18-1295. Epub 2020 Jan 8.
2
Insights into the human oral microbiome.对人类口腔微生物群的见解。
Arch Microbiol. 2018 May;200(4):525-540. doi: 10.1007/s00203-018-1505-3. Epub 2018 Mar 23.
3
A systematic review of Fusobacterium necrophorum-positive acute tonsillitis: prevalence, methods of detection, patient characteristics, and the usefulness of the Centor score.坏死梭杆菌阳性急性扁桃体炎的系统评价:患病率、检测方法、患者特征及森托评分的效用
Eur J Clin Microbiol Infect Dis. 2016 Dec;35(12):1903-1912. doi: 10.1007/s10096-016-2757-y. Epub 2016 Aug 27.
4
Incidence, risk factors, and outcomes of Fusobacterium species bacteremia.梭杆菌属菌血症的发生率、危险因素和结局。
BMC Infect Dis. 2013 Jun 5;13:264. doi: 10.1186/1471-2334-13-264.
5
Epidemiology and clinical outcomes of patients with Fusobacterium bacteraemia.梭杆菌菌血症患者的流行病学和临床结局。
Epidemiol Infect. 2013 Feb;141(2):325-9. doi: 10.1017/S0950268812000660. Epub 2012 Apr 17.
6
Fusobacterium nucleatum in periodontal health and disease.具核梭杆菌与牙周健康和疾病。
Curr Issues Mol Biol. 2011;13(2):25-36. Epub 2011 Jan 10.
7
Incidence and clinical epidemiology of necrobacillosis, including Lemierre's syndrome, in Denmark 1990-1995.1990 - 1995年丹麦坏死杆菌病(包括勒米尔氏综合征)的发病率及临床流行病学情况。
Eur J Clin Microbiol Infect Dis. 1998 Aug;17(8):561-5. doi: 10.1007/BF01708619.
8
Minimum inhibitory concentrations for selected antimicrobial agents against Fusobacterium necrophorum isolated from hepatic abscesses in cattle and sheep.从牛和羊肝脓肿中分离出的坏死梭杆菌对选定抗菌剂的最低抑菌浓度。
J Vet Pharmacol Ther. 1997 Feb;20(1):21-3. doi: 10.1046/j.1365-2885.1997.00043.x.
9
Meningitis due to Fusobacterium necrophorum subspecies necrophorum. Case report and review of the literature.
Infection. 1993 Jan-Feb;21(1):57-60. doi: 10.1007/BF01739317.
10
Infective endocarditis due to Fusobacterium nucleatum: case report and review of the literature.具核梭杆菌引起的感染性心内膜炎:病例报告及文献复习
Clin Cardiol. 1993 Jan;16(1):72-5. doi: 10.1002/clc.4960160116.