Niinimaa V, Shephard R J
J Gerontol. 1978 May;33(3):362-7. doi: 10.1093/geronj/33.3.362.
CO2 rebreathing measurements of cardiac output have been made in 8 men and 7 women aged 60--76 years, before and immediately after participation in an 11-week endurance training programme. Initial values showed a lower heart rate than in younger subjects at a given percentage of maximum oxygen intake. Stroke volume decreased slightly over the range of 40--80% of maximum oxygen intake. Relative to younger subjects, metabolic needs were thus met to a larger extent by a widening of arterio-venous oxygen difference and redistribution of blood flow. Over the period of observation, training induced a decrease in heart rate and cardiac output at a given sub-maximum work load, with no change in stroke volume or arterio-venous oxygen difference.