Bertelsen A, Gottesman I I
Department of Psychiatric Demography, Aarhus University Psychiatric Hospital, Denmark.
Am J Med Genet. 1995 Feb 27;60(1):7-11. doi: 10.1002/ajmg.1320600103.
The diagnostic classification of schizoaffective psychoses has varied much since Kasanin introduced the concept in 1933. The various classifications have agreed that schizoaffective psychoses present a combination of schizophreniform and affective symptoms, but the diagnostic criteria differ as to the number, quality, and time sequence of the symptoms even in recent classifications like RDC, DSM-III-R, and ICD-10. The classifications are syndromatical, and the etiology of the schizoaffective psychoses is still undetermined apart from evidence for a strong genetic factor. Results from family, twin, and adoption studies are divergent, but all the same, support a separate classification of broadly defined schizoaffective psychoses as possibly being phenotypical variations or expressions of genetic interforms between schizophrenia and affective psychoses.
自1933年卡沙宁提出精神分裂症-情感性精神病这一概念以来，其诊断分类变化很大。各种分类方法都认为，精神分裂症-情感性精神病呈现出精神分裂症样症状和情感症状的组合，但即使在像研究用诊断标准（RDC）、《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）和《国际疾病分类》第十版（ICD-10）这样的近期分类中，诊断标准在症状的数量、性质和时间顺序方面也存在差异。这些分类是基于综合征的，除了有强有力的遗传因素证据外，精神分裂症-情感性精神病的病因仍未确定。家族研究、双生子研究和收养研究的结果各不相同，但尽管如此，都支持将广义定义的精神分裂症-情感性精神病单独分类，因为它可能是精神分裂症和情感性精神病之间遗传中间形式的表型变异或表现。
