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[从遗传学观点看内源性精神病的分类]

[Classification of endogenous psychoses from a genetic viewpoint].

作者信息

Scharfetter C

出版信息

Schweiz Arch Neurol Neurochir Psychiatr. 1979;125(2):301-13.

PMID:555546
Abstract

The family-heredity findings serving as criteria for the classification of functional psychoses are discussed, presenting recent data. The global morbidity risk of the resp. psychosis showing secondary cases similar (homotypical) to the index case and no increased incidence of cases of the other type may be interpreted by the theory of two separated genetically transmitted diseases (schizophrenias and affective disorders). The classical schizophrenic subtypes differ in their global schizophrenia morbidity risk and show a tendency toward homotypical secondary cases. Monopolar and bipolar affective disorders were found to be very close together concerning family-genetic data-Schizo-affective psychotics were found to have among their relatives the highest incidence of all types of functional psychoses at all, a high rate of schizophrenics (esp. catatonic type) and affective psychotics and no homotypical secondary cases.

摘要

讨论了作为功能性精神病分类标准的家族遗传研究结果,并展示了近期数据。相应精神病的总体发病风险表现为,继发性病例与索引病例相似(同型),且其他类型病例的发病率未增加,这可以用两种独立的遗传传播疾病(精神分裂症和情感障碍)理论来解释。经典的精神分裂症亚型在总体精神分裂症发病风险上有所不同,并表现出同型继发性病例的倾向。就家族遗传数据而言,单极和双极情感障碍非常相似——分裂情感性精神病患者的亲属中,所有类型功能性精神病的发病率总体最高,精神分裂症患者(尤其是紧张型)和情感性精神病患者的比例很高,且没有同型继发性病例。

相似文献

1
[Classification of endogenous psychoses from a genetic viewpoint].[从遗传学观点看内源性精神病的分类]
Schweiz Arch Neurol Neurochir Psychiatr. 1979;125(2):301-13.
2
Subdividing the functional psychoses: a family hereditary approach.
Psychol Med. 1981 Aug;11(3):637-40. doi: 10.1017/s0033291700052910.
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[Depression and schizophrenia (author's transl)].[抑郁症与精神分裂症(作者译)]
Encephale. 1981;7(4 Suppl):343-6.
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Schizoaffective psychoses: genetical clues to classification.分裂情感性精神病:分类的遗传学线索
Am J Med Genet. 1995 Feb 27;60(1):7-11. doi: 10.1002/ajmg.1320600103.
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[Pattern of familial psychoses--systematic and unsystematic schizophrenia and cycloid psychoses].[家族性精神病模式——系统性和非系统性精神分裂症及循环型精神病]
Psychiatr Neurol Med Psychol (Leipz). 1975 Feb;27(2):80-100.
6
The genetic contribution to the functional psychoses.基因对功能性精神病的影响。
Br J Hosp Med. 1980 Aug;24(2):166, 169-71.
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Schizoaffective disorder merges schizophrenia and bipolar disorders as one disease--there is no schizoaffective disorder.分裂情感性障碍将精神分裂症和双相情感障碍合并为一种疾病——但实际上并不存在分裂情感性障碍。
Curr Opin Psychiatry. 2007 Jul;20(4):365-79. doi: 10.1097/YCO.0b013e3281a305ab.
8
[Clinico-genetic characteristics of psychoses with a clinical picture of involutional melancholia].[具有更年期忧郁症临床表现的精神病的临床遗传学特征]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(4):565-70.
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Schizo-affective disorder, manic type. A clinical, laboratory, and genetic study.分裂情感性障碍,躁狂型。一项临床、实验室及遗传学研究。
Psychiatr Clin (Basel). 1983;16(2-4):234-44.
10
[Genetics of endogenous psychoses].[内源性精神病的遗传学]
Schweiz Arch Neurol Neurochir Psychiatr. 1979;125(2):287-99.

引用本文的文献

1
Bipolar manic-depressive psychoses: results of a genetic investigation.双相躁狂抑郁症:一项遗传学调查的结果。
Hum Genet. 1980;55(2):237-54. doi: 10.1007/BF00291773.