运用连锁分析和体细胞定位将生长激素受体基因定位于牛的20号染色体。
Assignment of the growth hormone receptor gene to bovine chromosome 20 using linkage analysis and somatic cell mapping.
作者信息
Moody D E, Pomp D, Barendse W, Womack J E
机构信息
Department of Animal Science, Oklahoma State University, Stillwater 74078, USA.
出版信息
Anim Genet. 1995 Oct;26(5):341-3. doi: 10.1111/j.1365-2052.1995.tb02671.x.
Abstract
A polymorphism was identified in the bovine growth hormone receptor (GHR) gene by digesting polymerase chain reaction (PCR) products with the restriction enzyme Alul. Two alleles were segregating in cattle of Bos indicus descent, but one allele appears to be fixed in Bos taurus cattle. GHR was localized to bovine chromosome 20 using bovine-rodent hybrid cell lines and linkage analysis.
摘要
通过用限制性内切酶Alul消化聚合酶链反应（PCR）产物，在牛生长激素受体（GHR）基因中鉴定出一种多态性。在印度瘤牛后裔的牛中，两个等位基因发生分离，但在普通牛中一个等位基因似乎是固定的。利用牛-啮齿动物杂交细胞系和连锁分析将GHR定位到牛的20号染色体上。
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