Yakoun M
Clinique Saint-Jean, Montpellier.
Ann Fr Anesth Reanim. 1995;14 Suppl 2:47-53. doi: 10.1016/s0750-7658(95)80102-2.
Today a consensus on the value of peroperative nutritional support is not existing, despite a recognized correlation between the stage of denutrition and the postoperative mortality and morbidity rates. This review of 11 prospective randomized studies, comparing undernourished patients with a major malignant or non-malignant surgical illness, according to the use or not of preoperative nutritional support, showed a wide discrepancy between the techniques of denutrition assessment, the underlying surgical disease, the tumor extension, the extend of surgery, the level and duration of nutritional support between the studies. However, among them, those without major bias show that a preoperative nutritional support of at least seven days, decreases significantly the rate of postoperative complications, especially the infection, in the most undernourished patients.
尽管营养不良的程度与术后死亡率和发病率之间存在公认的相关性,但目前对于围手术期营养支持的价值尚未达成共识。这篇对11项前瞻性随机研究的综述,比较了患有严重恶性或非恶性外科疾病的营养不良患者,根据是否使用术前营养支持,结果显示这些研究在营养不良评估技术、潜在的外科疾病、肿瘤范围、手术范围、营养支持的水平和持续时间等方面存在很大差异。然而,在这些研究中,那些没有重大偏差的研究表明,对于营养不良最严重的患者,至少七天的术前营养支持可显著降低术后并发症的发生率,尤其是感染率。