Jóźwiak Z
Department of Thermobiology, University of Lódź, Poland.
Arch Immunol Ther Exp (Warsz). 1994;42(4):247-52.
A variety of cells subjected to hyperthermia acquire a transient increase in resistance (thermotolerance) to a subsequent heat treatment. The development of thermotolerance is nearly always accompanied by the presence of heat shock proteins (HSPs). However, other states of thermotolerance, some of which are independent of HSPs, have also been postulated. Recently, several studies have shown that cellular membranes, among other cellular structures, may be involved in the response of cells to heat and may constitute a target for the acquisition of thermal resistance.
多种受到热疗的细胞对随后的热处理会产生短暂的抗性增加（热耐受性）。热耐受性的发展几乎总是伴随着热休克蛋白（HSPs）的出现。然而，也有人推测存在其他热耐受性状态，其中一些与热休克蛋白无关。最近，几项研究表明，细胞膜以及其他细胞结构可能参与细胞对热的反应，并且可能构成获得热抗性的靶点。
