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男性腹部脂肪分布与冠心病危险因素——腰高比作为一种简单实用的预测指标

Abdominal fat distribution and coronary heart disease risk factors in men-waist/height ratio as a simple and useful predictor.

作者信息

Hsieh S D, Yoshinaga H

机构信息

Medical Center of Health Science, Toranomon Hospital, Tokyo, Japan.

出版信息

Int J Obes Relat Metab Disord. 1995 Aug;19(8):585-9.

PMID:7489031
Abstract

OBJECTIVE

To determine whether waist/height ratio is a useful predictor for coronary heart disease (CHD) risk factors in men.

DESIGN

An epidemiologic study comparing relationships between waist/height ratio, body mass index, waist/hip ratio and CHD risk factor levels [continuous variables--systolic and dialostic blood pressure, fasting blood glucose, hemoglobin A1c (HbA1c), triglyceride, cholesterol, HDL cholesterol values] and the risk factor morbidity index (sum of the risk factor scores for hypertension, abnormal glucose tolerance, hypertriglyceridemia, hypercholesterolemia and low HDL cholesterol--one point each if present).

SETTING

A health examination facility within a general hospital.

SUBJECTS

3131 men underwent routine health examination.

RESULTS

Body mass index, waist/hip ratio and waist/height ratio were significantly associated with all of the risk factor levels and with the risk factor morbidity index according to the result of simple regression analysis. Multiple regression analysis for waist/hip ratio and body mass index showed that both of them were also significantly associated with all of the risk factor levels and with the risk factor morbidity index, except HbA1c levels with body mass index. According to the results of multiple regression analysis for waist/height ratio and body mass index, body mass index was not significantly associated with fasting blood glucose, HbA1c, cholesterol levels or the risk factor morbidity index whereas waist/height ratio was significantly associated with all of the variables. On the other hand, while waist/height ratio was significantly associated with all of the variables, waist/hip ratio was not significantly associated with most of the variables when waist/height ratio and waist/hip ratio were compared.

CONCLUSION

Waist/height ratio, an index of abdominal obesity, may be a better predictor of multiple CHD risk factors in men than waist/hip ratio in mass epidemiologic studies.

摘要

目的

确定腰高比是否为男性冠心病(CHD)危险因素的有效预测指标。

设计

一项流行病学研究,比较腰高比、体重指数、腰臀比与冠心病危险因素水平[连续变量——收缩压和舒张压、空腹血糖、糖化血红蛋白(HbA1c)、甘油三酯、胆固醇、高密度脂蛋白胆固醇值]以及危险因素发病指数(高血压、糖耐量异常、高甘油三酯血症、高胆固醇血症和低高密度脂蛋白胆固醇的危险因素得分总和——如有则各计1分)之间的关系。

地点

一家综合医院内的健康检查机构。

研究对象

3131名男性接受了常规健康检查。

结果

根据简单回归分析结果,体重指数、腰臀比和腰高比均与所有危险因素水平及危险因素发病指数显著相关。对腰臀比和体重指数进行多元回归分析表明,二者也均与所有危险因素水平及危险因素发病指数显著相关,但体重指数与HbA1c水平除外。根据对腰高比和体重指数进行的多元回归分析结果,体重指数与空腹血糖、HbA1c、胆固醇水平或危险因素发病指数无显著相关性,而腰高比与所有这些变量均显著相关。另一方面,虽然腰高比与所有变量均显著相关,但在比较腰高比和腰臀比时,腰臀比与大多数变量无显著相关性。

结论

在大规模流行病学研究中,作为腹部肥胖指标的腰高比可能比腰臀比更能有效预测男性的多种冠心病危险因素。

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