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年轻成年人腹部高度与心血管危险因素的关系:博加卢萨心脏研究

Relation of abdominal height to cardiovascular risk factors in young adults: the Bogalusa heart study.

作者信息

Gustat J, Elkasabany A, Srinivasan S, Berenson G S

机构信息

Tulane Center for Cardiovascular Health, Tulane University Medical Center, New Orleans, LA, USA.

出版信息

Am J Epidemiol. 2000 May 1;151(9):885-91. doi: 10.1093/oxfordjournals.aje.a010292.

Abstract

Obesity and fat patterns are important predictors of coronary heart disease risk. The relations of abdominal height (sagittal diameter) and various obesity measures to coronary heart disease risk factors were examined in a community-based sample of 409 Blacks and 1,011 Whites aged 20-38 years in Bogalusa, Louisiana (1995-1996). Obesity measures used included weight, waist circumference, waist:hip ratio, waist:height ratio, abdominal height, triceps and subscapular skinfold thicknesses, body mass index, and conicity index. Abdominal height was highly correlated with other obesity measures, especially waist circumference (0.937-0.944, p < 0.001), and was least correlated with height. In multivariate analysis, abdominal height was an independent predictor of levels of total cholesterol, triglycerides, very low density lipoprotein cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, glucose, and insulin and of systolic and diastolic blood pressures (p < 0.05 to p < 0.001), with total R2 values ranging from 0.13 to 0.52. Abdominal height contributed more to the prediction of blood pressure than did other measures of central obesity. In canonical analysis, abdominal height was correlated more strongly with the coronary disease risk factor variables as a group than were other obesity measures. These results suggest that abdominal height adds another dimension to measures of obesity in that it may help to assess a component of visceral fat that other measures miss.

摘要

肥胖及脂肪分布模式是冠心病风险的重要预测指标。在路易斯安那州博加卢萨市(1995 - 1996年),对409名20 - 38岁的黑人和1011名白人组成的社区样本,研究了腹高(矢状径)及各种肥胖指标与冠心病风险因素之间的关系。所使用的肥胖指标包括体重、腰围、腰臀比、腰高比、腹高、肱三头肌和肩胛下皮褶厚度、体重指数及锥度指数。腹高与其他肥胖指标高度相关,尤其是腰围(0.937 - 0.944,p < 0.001),与身高的相关性最小。在多变量分析中,腹高是总胆固醇、甘油三酯、极低密度脂蛋白胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、血糖、胰岛素水平以及收缩压和舒张压的独立预测指标(p < 0.05至p < 0.001),总R²值范围为0.13至0.52。腹高对血压预测的贡献比其他中心性肥胖指标更大。在典型分析中,腹高与冠心病风险因素变量组的相关性比其他肥胖指标更强。这些结果表明,腹高为肥胖测量增加了另一个维度,因为它可能有助于评估其他测量方法遗漏的内脏脂肪成分。

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