Jaffe N, Patel S R, Benjamin R S
University of Texas Medical School at Houston, USA.
Hematol Oncol Clin North Am. 1995 Aug;9(4):825-40.
Chemotherapy in osteosarcoma has had a major impact in attaining metastasis-free survival, and the cure rates with the use of modern regimens range from 65% to 75%. Preoperative chemotherapy has facilitated surgical resection of the primary tumor, rendering increased numbers of candidates for limb salvage. The effects on the primary tumor may be used as a predictive factor in determining outcome.
骨肉瘤的化疗对实现无转移生存产生了重大影响，采用现代治疗方案的治愈率在65%至75%之间。术前化疗有助于对原发性肿瘤进行手术切除，使更多适合保肢手术的患者成为可能。对原发性肿瘤的治疗效果可作为判断预后的一个预测因素。
