Lin C L, Lieu A S, Kwan A L, Howng S L
Department of Neurosurgery, Kaohsiung Medical College, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1995 Nov;11(11):633-6.
Primary intracranial yolk sac tumor (Endodermal sinus tumor, YST) is quite rare, and most usually involves the pineal gland. This report concerns a rare case of unknown origin of yolk sac tumor with intracranial and spinal metastases. The 6-year-old boy initially manifested symptoms of acute urinary retension and paraparesis. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed an intrathecal tumor spreading below the third lumbar segment, and tumors also appeared in the left temporal area and right cerebellar hemisphere. The pineal region was free of neoplastic involvement and the gonads were normal. The patients underwent operation to remove intracranial and spinal tumors, and postoperative radiotherapy was administered. The histological findings showed metastatic yolk sac tumor. Multiple intracranial and spinal seeding were noticed postoperatively. The patient died of recurrent YST and pneumonia three months after operation. The origin of secondary YST can always be found in specific midline sites. This is a rare case since the primary lesion is unknown.
原发性颅内卵黄囊瘤（内胚窦瘤，YST）非常罕见，最常累及松果体。本报告涉及一例罕见的不明起源的卵黄囊瘤伴颅内和脊髓转移病例。这名6岁男孩最初表现为急性尿潴留和双下肢轻瘫症状。计算机断层扫描（CT）和磁共振成像（MRI）显示鞘内肿瘤蔓延至第三腰椎以下节段，左侧颞叶区和右侧小脑半球也出现肿瘤。松果体区未受肿瘤累及，性腺正常。患者接受了颅内和脊髓肿瘤切除术，并进行了术后放疗。组织学检查结果显示为转移性卵黄囊瘤。术后发现多处颅内和脊髓播散。患者术后三个月死于复发性YST和肺炎。继发性YST的起源总能在特定的中线部位找到。这是一例罕见病例，因为原发灶不明。
