Kurisaka M, Moriki A, Mori K, Sonobe H
Department of Neurosurgery, Kochi Medical School, Nankoku-city, Japan.
Childs Nerv Syst. 1998 Nov;14(11):653-7. doi: 10.1007/s003810050293.
A case of a primary yolk sac tumor of the spinal cord is reported. The patient was a 17-month-old Japanese girl, who was found to have an intramedullary mass at the upper thoracic level. The preoperative diagnosis was primary glioma, but histological examination of the surgical specimen revealed a yolk sac tumor. As there were no other lesions, the spinal cord lesion was considered to be the primary tumor. Based on our previous experience, we treated this patient with low-dose irradiation followed by combination chemotherapy with cisplatin, vinblastine and bleomycin. However, the effectiveness of this therapy was poor in this particular case, and the patient died of pyelonephritis with uncontrollable imbalance of serum electrolytes.
报告了一例脊髓原发性卵黄囊瘤病例。患者为一名17个月大的日本女孩，发现上胸段髓内有一肿块。术前诊断为原发性神经胶质瘤，但手术标本的组织学检查显示为卵黄囊瘤。由于没有其他病变，脊髓病变被认为是原发性肿瘤。根据我们之前的经验，我们对该患者采用低剂量放疗，随后顺铂、长春碱和博来霉素联合化疗。然而，在这个特殊病例中，这种治疗效果不佳，患者死于肾盂肾炎，血清电解质失衡无法控制。
