Boyle P, Maisonneuve P, Steg A
Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy.
J Urol. 1996 Jan;155(1):176-80.
A systematic examination of all available mortality data from benign prostatic hyperplasia (BPH) between 1950 and 1990 was done to estimate the changing international mortality pattern of this condition.
Mortality data in which BPH was the underlying cause of death were abstracted from the World Health Organization mortality data base. These data were available from a variety of international countries (in many since 1950).
Mortality rates have decreased with considerable magnitude in developed western countries between the early 1950s and late 1980s. This fact could reasonably be attributed to the improved management of the most severe complications of BPH and to improvements in surgery and anesthesia, which have made surgical interventions of the prostate possible in a greater proportion of men, and safer in the immediate and subsequent postoperative period.
The decreases noted in western countries, such as the United Kingdom (where 8,700 fewer men die each year presently than would be expected if the BPH mortality rates from the early 1950s still applied), United States (13,681 fewer deaths) and France (2,884 fewer deaths), indicate a considerable but unheralded achievement for modern medicine. Unfortunately, these decreases have not been observed to the same extent in central and eastern Europe and South America, where the residual high mortality rates could be lowered by education, and the widespread availability of modern surgical and anesthetic equipment.
对1950年至1990年间所有可获得的良性前列腺增生（BPH）死亡率数据进行系统审查，以估计这种疾病在国际上不断变化的死亡率模式。
从世界卫生组织死亡率数据库中提取以BPH为根本死因的死亡率数据。这些数据来自多个国家（许多国家自1950年起就有数据）。
在20世纪50年代初至80年代末期间，西方发达国家的死亡率有相当大幅度的下降。这一事实合理地归因于BPH最严重并发症管理的改善以及手术和麻醉技术的进步，这使得更大比例的男性能够接受前列腺手术，并且在手术即刻及术后更安全。
在西方国家观察到的死亡率下降情况，如英国（目前每年死于BPH的男性比如果仍采用20世纪50年代初的死亡率预期少8700人）、美国（少13681人死亡）和法国（少2884人死亡），表明现代医学取得了一项相当可观但未被广泛宣扬的成就。不幸的是，在中欧、东欧和南美洲并未观察到同样程度的下降，在这些地区，通过教育以及广泛提供现代手术和麻醉设备，可以降低仍然较高的死亡率。
