Metzger J, Buge A, Rancurel G, Gardeur D
Rev Neurol (Paris). 1978 Oct;134(10):619-24.
A study of 3 cases of acute bismuth encephalopathy by C. T. scanner revealed indisputable evidence of abnormal hyperdensity in certain brain regions. These hyperdensities, or rather hyperattenuations, are very typical in case no. 1, where the central grey nuclei, especially the caudate nuclei and cerebral cortex, have an important hyperdence appearance. The images are heterogenous, sometimes granular, and are not modified by the injection of a contrast medium. There are also ventricular and cisternal dilatations which are even more remarkable when the age of the patients (less than 45 years) is considered. Cases Nos. 2 and 3 showed hyperdensity which was mainly in the cortical hemispheres. Blood bismuth levels vary according to the date of bismuth stoppage, lying between 850 and 1.350 microgram p. 1.000 ml. The pathogenesis of these tomodensitometric images are discussed as a function the of atomic number of bismuth metal and its unequal distribution in the cerebral parenchyma and the meninges.
一项利用CT扫描仪对3例急性铋中毒性脑病的研究揭示了某些脑区存在异常高密度的无可争议的证据。这些高密度影，或者更确切地说是高衰减影，在病例1中非常典型，其中央灰质核，尤其是尾状核和大脑皮层，呈现出明显的高密度外观。图像不均匀，有时呈颗粒状，注射造影剂后无变化。还存在脑室和脑池扩张，考虑到患者年龄（小于45岁）时，这种扩张更为明显。病例2和病例3显示高密度影主要位于大脑半球皮质。血铋水平根据铋停用日期而有所不同，每1000毫升血液中铋含量在850至1350微克之间。根据铋金属的原子序数及其在脑实质和脑膜中分布不均的情况，对这些CT图像的发病机制进行了讨论。
