Escourolle R, Bourdon R, Galli A, Galle P, Jaudon M C, Hauw J J, Gray F
Rev Neurol (Paris). 1977 Mar;133(3):153-63.
Examination of twelve cases of bismuth encephalopathy showed a constantand marked elevation of the bismuth levels in autopsy cerebral tissue (ranging from 2-8 mg/kg to 25 mg/kg). These values were found to be much higher than the last-measured Bismuth venous blood values. In every case, periveinular lymphocytic infiltration and abundant intra-cytoplasmic lipofuscin were seen. The microanalysis with Castaing's electrode revealed the presence of focal areas of bismuth in the leptomeningeal spaces. The significance of the lesions is not fully established and it will undergo further investigations.
对12例铋中毒性脑病患者的检查显示，尸检脑组织中的铋含量持续且显著升高（范围从2 - 8毫克/千克至25毫克/千克）。这些值远高于最后测量的铋静脉血值。在每例病例中，均可见静脉周围淋巴细胞浸润和丰富的胞浆内脂褐素。用卡斯廷电极进行的微量分析显示，软脑膜间隙存在局灶性铋沉积区。这些病变的意义尚未完全明确，将进一步开展研究。
