Burg J R, Gist G L
Exposure and Disease Registry Branch, Agency for Toxic Substances and Disease Registry, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia.
Toxicol Ind Health. 1995 Mar-Apr;11(2):231-48. doi: 10.1177/074823379501100209.
The Agency for Toxic Substances and Disease Registry has, as mandated in Superfund legislation, established the National Exposure Registry (NER). The purpose of the NER is to assess and evaluate the potential relationship between adverse health effects and environmental exposure for an exposed population, particularly the relationship between chronic health effects and long-term, low-level chemical exposures. The NER's primary goal is to facilitate epidemiology research by establishing multiple data bases (subregistries) that contain demographic, environmental, and health information on large populations exposed to selected chemicals. The Registry data mainly serve the purpose of being hypothesis-generating rather than hypothesis-testing. The NER is currently composed of subregistries of: (1) persons exposed to volatile organic compounds (VOCs)--a subset of registrants in whom trichloroethylene (TCE) is the primary VOC exposure, but others are present (N = 4,832), a subset in whom benzene is the primary VOC exposure (N = 1,142), and a subset in whom trichloroethane (TCA) and TCE are the highest VOC exposures (N = 3,666); and (2) persons with dioxin exposure (N = 250). Chromium and radioactive substances subregistries are planned.
根据《超级基金法》的规定，有毒物质与疾病登记署设立了国家暴露登记处（NER）。NER的目的是评估和评价受暴露人群的健康不良影响与环境暴露之间的潜在关系，特别是慢性健康影响与长期低水平化学物质暴露之间的关系。NER的主要目标是通过建立多个数据库（子登记处）来促进流行病学研究，这些数据库包含了接触特定化学物质的大量人群的人口统计学、环境和健康信息。登记处的数据主要用于生成假设，而非检验假设。NER目前由以下子登记处组成：（1）接触挥发性有机化合物（VOCs）的人群——一部分登记者主要接触三氯乙烯（TCE），但也接触其他VOCs（N = 4832），一部分主要接触苯（N = 1142），还有一部分三氯乙烷（TCA）和TCE的暴露水平最高（N = 3666）；（2）接触二恶英的人群（N = 250）。铬和放射性物质子登记处正在规划中。
