Couzy F, Kastenmayer P, Vigo M, Clough J, Munoz-Box R, Barclay D V
Nestlé Research Centre, NESTEC Ltd, Lausanne, Switzerland.
Am J Clin Nutr. 1995 Dec;62(6):1239-44. doi: 10.1093/ajcn/62.6.1239.
Some mineral waters have a high calcium content and may contribute a significant part of the human daily requirements. Calcium bioavailability from a calcium- and sulfate-rich mineral water (CS-W) containing 11.2 mmol Ca/L (467 mg/L) was compared with that from milk in nine healthy young women. Calcium absorption was measured in the fasting state with a dual-label stable-isotope technique. Fractional absorption rates from milk and CS-W were 25.0 +/- 6.7% and 23.8 +/- 4.8% (means +/- SD), respectively, and did not differ significantly (P = 0.05). Urine was collected for 36 h after the administration of the oral stable isotope while the subjects consumed a controlled diet and a quantity of milk or CS-W providing 25 mmol (1000 mg) Ca. No significant difference was found in the excretion of calcium, nor in the excretion of the two stable isotopes. Mean urinary sulfate excretion was significantly increased by 35% when the CS-W was consumed. No significant correlation was found between 36-h urinary excretion of the intravenous calcium tracer and sulfate, sodium, or urine volume. Therefore, calcium from the CS-W was as well absorbed and retained as that from milk, and no calciuric effect of sulfate was found, showing that such mineral waters can be valuable dietary sources of calcium.
一些矿泉水中钙含量很高，可能占人体每日需求量的很大一部分。在9名健康年轻女性中，对一种钙和硫酸盐含量丰富的矿泉水（CS-W，含钙11.2 mmol/L（467 mg/L））的钙生物利用度与牛奶的钙生物利用度进行了比较。采用双标记稳定同位素技术在空腹状态下测量钙吸收情况。牛奶和CS-W的分数吸收率分别为25.0±6.7%和23.8±4.8%（均值±标准差），两者无显著差异（P = 0.05）。在口服稳定同位素后收集36小时尿液，同时受试者食用对照饮食以及一定量提供25 mmol（1000 mg）钙的牛奶或CS-W。在钙排泄以及两种稳定同位素的排泄方面均未发现显著差异。饮用CS-W时，平均尿硫酸盐排泄量显著增加了35%。静脉注射钙示踪剂的36小时尿排泄量与硫酸盐、钠或尿量之间未发现显著相关性。因此，CS-W中的钙与牛奶中的钙吸收和保留情况一样好，且未发现硫酸盐的促钙尿作用，表明此类矿泉水是有价值的膳食钙源。
