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[现代联合化疗条件下晚期恶性淋巴瘤的可治愈性]

[Curability of advanced malignant lymphoma under conditions of modern combination chemotherapy].

作者信息

Viollier A F, Senn H J, Obrecht J P

出版信息

Schweiz Med Wochenschr. 1978 Dec 9;108(49):1958-61.

PMID:749192
Abstract

102 patients from the same oncologic center with malignant lymphomas (52 with Hodgkin's disease, 50 with non-Hodgkin lymphomas) have been analyzed. One population received monochemotherapy only and the other polychemotherapy: the first remission and survival results were published in 1975 on the basis of calculated life expectancy. Now, 3 years later, the same populations are again analyzed and "real" survival data are compared with those calculated. All patients now have a minimal observation time of 6 years. Even if our first published data were too optimistic, polychemotherapy still appears to offer the better life expectancy.

摘要

对来自同一肿瘤中心的102例恶性淋巴瘤患者(52例霍奇金病,50例非霍奇金淋巴瘤)进行了分析。一组仅接受单一化疗,另一组接受联合化疗:首次缓解和生存结果于1975年根据计算出的预期寿命公布。现在,3年后,再次对相同人群进行分析,并将“实际”生存数据与计算数据进行比较。所有患者目前的最短观察时间为6年。即使我们首次公布的数据过于乐观,联合化疗似乎仍能提供更好的预期寿命。

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