Beath S V, Booth I W, Murphy M S, Buckels J A, Mayer A D, McKiernan P J, Kelly D A
Institute of Child Health, University of Birmingham.
Arch Dis Child. 1995 Oct;73(4):348-50. doi: 10.1136/adc.73.4.348.
Twenty two children were evaluated for small bowel transplantation between 1989 and 1994. Eight were unfit for transplantation and died within three months; a raised plasma bilirubin concentration (> 200 mumol/l) predicted death from liver failure within six months (p = 0.0001). The 11 children who were not managed by a multidisciplinary nutritional care team were less well nourished at referral, had more complications with intravenous feeding catheters, and greater early mortality while awaiting transplantation (p < 0.05). It is recommended that children with chronic intestinal failure be referred for assessment early, before liver dysfunction is established.
1989年至1994年间,对22名儿童进行了小肠移植评估。其中8名儿童不适合进行移植,在三个月内死亡;血浆胆红素浓度升高(>200 μmol/L)预示着六个月内死于肝功能衰竭(p = 0.0001)。11名未由多学科营养护理团队管理的儿童在转诊时营养状况较差,静脉喂养导管相关并发症更多,等待移植期间早期死亡率更高(p < 0.05)。建议慢性肠衰竭儿童在肝功能障碍确立之前尽早转诊进行评估。