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聚合型N-乙酰-D-葡萄糖胺(几丁质)可在犬体内诱导前列腺素E2的产生。

Polymeric N-acetyl-D-glucosamine (chitin) induces prostaglandin E2 in dogs.

作者信息

Minami S, Okamoto Y, Matsuhashi A, Sashiwa H, Saimoto H, Shigemasa Y, Tanigawa T, Suzuki T, Tanioka S, Tanaka Y

机构信息

Department of Veterinary Surgery, Faculty of Agriculture, Tottori University, Japan.

出版信息

J Vet Med Sci. 1995 Apr;57(2):377-8. doi: 10.1292/jvms.57.377.

DOI:10.1292/jvms.57.377
PMID:7492669
Abstract

The level of prostaglandin E2 (PGE2) in the exudate induced by subcutaneous implantation of a complex formed from non-woven fabric of polyester (NWF) and polymeric N-acetyl-D-glucosamine (chitin) (chitin/NWF) or by implantation of NWF in dogs was measured by radioimmunoassay. The amount of PGE2 in the exudate induced by chitin/NWF was about five times as high as that in the exudate induced by NWF (p < 0.05), while the level of PGE2 in the exudate was similar to that in serum.

摘要

采用放射免疫分析法测定了聚酯无纺布(NWF)与聚合N-乙酰-D-葡萄糖胺(几丁质)(几丁质/NWF)形成的复合物皮下植入或NWF植入犬体内所诱导的渗出液中前列腺素E2(PGE2)的水平。几丁质/NWF诱导的渗出液中PGE2的含量约为NWF诱导的渗出液中PGE2含量的五倍(p < 0.05),而渗出液中PGE2的水平与血清中的相似。

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