Gross A J, Berg P H
Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston, USA.
J Expo Anal Environ Epidemiol. 1995 Apr-Jun;5(2):181-95.
The concern that use of talc or talc-containing substances in the perineal region of women may subject them to an increased risk for ovarian cancer has become an important issue in the study of ovarian cancer. The purpose of this paper is to examine whether this concern, heightened by several epidemiological studies purporting to show an increased risk, is valid. Epidemiological studies examining the possibility of this relationship are reviewed, and meta-analyses of their results are performed. The conclusion reached herein is that the evidence regarding the risk of ovarian cancer associated with talc exposure is equivocal, and further examination of the relationship is required before a sound conclusion can be made.
女性会阴区域使用滑石粉或含滑石粉物质可能使她们患卵巢癌风险增加，这一担忧已成为卵巢癌研究中的一个重要问题。本文旨在探讨这一因多项流行病学研究称显示风险增加而加剧的担忧是否合理。对检验这种关系可能性的流行病学研究进行了综述，并对其结果进行了荟萃分析。本文得出的结论是，关于滑石粉暴露与卵巢癌风险的证据并不明确，在得出可靠结论之前，需要对这种关系进行进一步研究。
